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SONAR Targetspace for AVOCATIN AZ-score WebGraph NB WebGraph
Targetspace hs 127 0
Targetspace hs pval0.294573643410851
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   4 30   0
HLJ1 YMR161W Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p pro...   4 102   0
  YMR073C     3 23   0
ARC18 YLR370C Subunit of the ARP2/3 complex, which is required for the motility and integrity ...   3 81 -1.1505 0.0534
RAD10 YML095C Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA durin... ssDNA endonuclease 3 32   0
SMY1 YKL079W Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-term... kinesin heavy chain homolog 3 29   0
RVB2 YPL235W Essential protein involved in transcription regulation; component of chromatin r... transcriptional regulator 3 20   0.0103
APL2 YKL135C Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; b... beta-adaptin|clathrin associated protein complex large subunit 3 19   0
ORM2 YLR350W Evolutionarily conserved protein with similarity to Orm1p, required for resistan... Endoplasmic reticulum membrane-anchored protein 3 51   0
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton o... rho GTPase activating protein (GAP) 3 22   0.0981
BMH2 YDR099W 14-3-3 protein, minor isoform; binds proteins and DNA, involved in regulation of... member of conserved eukaryotic 14-3-3 gene family 3 29   0
WSS1 YHR134W Sumoylated protein of unknown function, identified based on genetic interactions...   2 28   0.0061
RGA1 YOR127W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... rho GTPase activating protein (GAP) 2 17   0.1639
UPC2 YDR213W Sterol regulatory element binding protein, induces transcription of sterol trans... zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type 2 24   0
TOA1 YOR194C TFIIA large subunit; involved in transcriptional activation, acts as antirepress... transcription factor IIA subunit alpha 2 9   0
YPT32 YGL210W GTPase of the Ypt/Rab family, very similar to Ypt31p; involved in the exocytic p... GTPase|YPT31 homolog|ras homolog 2 23   0.1242
CHS2 YBR038W Chitin synthase II, requires activation from zymogenic form in order to catalyze... chitin synthase 2 2 2   0.0831
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involv... GTP-binding protein|rho subfamily 2 26   0.1895
PXL1 YKR090W LIM domain-containing protein that localizes to sites of polarized growth, requi...   2 4   0.1236
TOA2 YKL058W TFIIA small subunit; involved in transcriptional activation, acts as antirepress... beta|transcription factor IIA subunit 2 11   0
TRM2 YKR056W tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs... tRNA methyltransferase 2 6   0.1154
RSR1 YGR152C GTP-binding protein of the ras superfamily required for bud site selection, morp...   2 27   0
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... ADP-ribosylation factor GTPase-activating protein (ARF GAP) 2 95   0
SBE2 YDR351W Protein involved in the transport of cell wall components from the Golgi to the ...   2 7   0.0006
EMP24 YGL200C Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicl... type I transmembrane protein 2 25   0
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli ... mitochondrial ribosomal protein L2 of the large subunit 2 18   0.0191
SEM1 YDR363W-A Component of the lid subcomplex of the regulatory subunit of the 26S proteasome;...   2 43   0
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active...   2 60   0.2442
PIH1 YHR034C Protein of unresolved function; may function in protein folding and/or rRNA proc...   2 14   0.0787
DOA4 YDR069C Ubiquitin hydrolase, required for recycling ubiquitin from proteasome-bound ubiq... ubiquitin isopeptidase 2 75 0.6043 0.166
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   2 25   0.0055
LEA1 YPL213W Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically int...   2 31   0.004
BUD16 YEL029C Protein involved in bud-site selection and telomere maintenance; diploid mutants...   2 10   0.1202
UBA4 YHR111W Protein that activates Urm1p before its conjugation to proteins (urmylation); on...   2 43   0.0208
RMI1 YPL024W Involved in response to DNA damage; null mutants have increased rates of recombi...   2 44   0.0001
HTB1 YDR224C One of two nearly identical (see HTB2) histone H2B subtypes required for chromat... histone H2B (HTB1 and HTB2 code for nearly identical proteins) 2 28   0.2186
FAT1 YBR041W Fatty acid transporter and very long-chain fatty acyl-CoA synthetase, may form a... fatty acid transporter 2 25   0.1881
SLA2 YNL243W Transmembrane actin-binding protein involved in membrane cytoskeleton assembly a... transmembrane protein 2 64   0.0304
ROM1 YGR070W GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal wit...   2 11   0.018
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and ... ribosomal protein S8A (S14A) (rp19) (YS9) 2 8   0.0472

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