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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SPC2 YML055W Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyz... signal peptidase complex subunit|similar to mammalian protein SPC25 2 45   0
TIR3 YIL011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins... cell wall mannoprotein 2 3   0
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   2 30   0
HXT8 YJL214W Protein of unknown function with similarity to hexose transporter family members... hexose permease 2 13   0
SEL1 YML013W UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 86   0.2689
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   2 64   0
PMT1 YDL095W Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphat... dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase 2 55   0.1912
ELF1 YKL160W Transcription elongation factor that contains a conserved zinc finger domain; im...   2 19   0
ERP2 YAL007C Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; memb... p24 protein involved in membrane trafficking 2 34   0
ATG8 YBL078C Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, a... similar to LC3, a microtubule-associated protein from rat 2 20   0
NPL4 YBR170C Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p ...   2 26   0.0051
CYS3 YAL012W Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the tr... cystathionine gamma-lyase 2 61   0
UBX4 YMR067C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 37   0.004
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition ... mannosyltransferase 2 49   0.2114
GOT1 YMR292W Evolutionarily conserved non-essential protein present in early Golgi cisternae ... membrane protein 2 34   0
MDM38 YOL027C Mitochondrial inner membrane protein, required for K+/H+ exchange and for normal...   1 8   0.0001
NRD1 YNL251C RNA-binding protein that interacts with the C-terminal domain of the RNA polymer...   1 11   0
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of th... TFIIF interacting component of CTD phosphatase 1 25   0.2497
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   1 25   0.0012
CET1 YPL228W Beta (RNA 5--triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (... RNA 5--triphosphatase|mRNA capping enzyme beta subunit (80 kDa) 1 8   0.0002
UBP2 YOR124C Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, ... ubiquitin-specific protease 1 7   0
THR4 YCR053W Threonine synthase, conserved protein that catalyzes formation of threonine from... threonine synthase 1 12   0.0533
SHM1 YBR263W Mitochondrial serine hydroxymethyltransferase, involved in one-carbon metabolism   1 13   0.006
RVB2 YPL235W Essential protein involved in transcription regulation; component of chromatin r... transcriptional regulator 1 20   0.0006
RVB1 YDR190C Essential protein involved in transcription regulation; component of chromatin r...   1 13   0.0232
LIP2 YLR239C Lipoyl ligase, involved in the modification of mitochondrial enzymes by the atta... Lipoyl ligase 1 11   0.0134
MRPS8 YMR158W Mitochondrial ribosomal protein of the small subunit   1 1   0.0002
BUD13 YGL174W Subunit of the RES complex, which is required for nuclear pre-mRNA retention and...   1 7   0.2337
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the dire... pyruvate dehydrogenase alpha subunit (E1 alpha) 1 10   0.0687
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export; DEAD-box RNA hel... ATP-dependent RNA helicase 1 35   0.0164
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evoluti... pyruvate dehydrogenase beta subunit (E1 beta) 1 6   0.3798
VID30 YGL227W Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-...   1 5   0
MTM1 YGR257C Mitochondrial protein of the mitochondrial carrier family, involved in activatin... putative mitochondrial carrier protein 1 2   0.0003
  YLR168C     1 10   0.0001
PET309 YLR067C Specific translational activator for the COX1 mRNA, also influences stability of...   1 8   0.3016
ERV41 YML067C Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involve...   1 13   0
MDM35 YKL053C-A Protein of unknown function; mutation affects mitochondrial distribution and mor...   1 6   0
GLY1 YEL046C Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine t... threonine aldolase 1 7   0.2816
ALT2 YDR111C Putative alanine transaminase (glutamic pyruvic transaminase)   1 8   0
MGM1 YOR211C Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p a... GTP-binding domain protein related to dynamin 1 8   0.0659

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