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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:34
Sym Orf Description Function No All Z_score hyperg
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 13 143 -15.5265 0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 11 33   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 10 24 -11.9241 0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   10 15   0.0832
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38   0.1393
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -16.6188 0.14
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 10 36   0.0391
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   10 34   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 10 25 -18.1100 NAN
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   8 51 -0.6836 0
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   8 98 -25.6235 0
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 7 104   0.0204
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   7 89   0.0002
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   7 109   0
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 7 74   NAN
AHA1 YDR214W Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to ... Hsp90 system cochaperone; Aha1 binds to the middle domain of Hsp90 and improves client protein activation in vivo 7 51   0
PIL1 YGR086C Integral membrane protein that along with Lsp1p is a primary component of eisoso...   7 80   0
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 6 41   0
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid required for ... proteasome regulatory particle subunit 6 66   0.0058
EGD2 YHR193C Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) in... GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog 6 33   0
PRE3 YJL001W 20S proteasome beta-type subunit, responsible for cleavage after acidic residues... 20S proteasome subunit 6 39   0
OYE2 YHR179W Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), ho... NAPDH dehydrogenase (old yellow enzyme), isoform 2 6 25   0
ILV5 YLR355C Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-ch... acetohydroxyacid reductoisomerase 6 17   0
RPT3 YDR394W One of six ATPases of the 19S regulatory particle of the 26S proteasome involved...   6 99   0
CBF5 YLR175W Component of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), pr... major low affinity 55 kDa centromere/microtubule binding protein 6 117   0.0001
SOG2 YOR353C Protein required for cell morphogenesis and cell separation after mitosis   5 10   0
WSP1 YOR220W protein that interacts genetically with the Pat1 mRNA-decapping factor   5 8   0
SSK2 YNR031C MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; intera... MAP kinase kinase kinase|activator of Pbs2p 5 34   0.0001
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer, u... phenylalanyl-tRNA synthetase alpha subunit 5 6   0
  YPL077C     5 22   0.0114
GCN3 YKR026C Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide... eIF2B 34 kDa alpha subunit 5 52 -5.0426 0

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