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SONAR Targetspace for GAMBOGIC ACID AMIDEZ-score WebGraph NB WebGraph
Targetspace hs 133 262
Targetspace hs pval0.201438848920860.81521739130435
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
CKB1 YGL019W Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles ... protein kinase CK2 beta subunit 5 83   0.0135
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polyme...   4 128   0.137
BUD14 YAR014C Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cort...   4 74   0.0016
CKA2 YOR061W Alpha- catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles... protein kinase CK2 alpha- subunit 3 128 -1.3221 0
PSY2 YNL201C Nuclear protein of unknown function; deletion results in sensitivity to anticanc...   3 34   0.2341
ARP7 YPR034W Actin-related protein involved in transcriptional regulation; subunit of the chr... actin related protein|chromatin remodeling Snf/Swi complex subunit 3 64   0
CEG1 YGL130W Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, a heterodimer (t... mRNA capping enzyme alpha subunit|mRNA guanylyltransferase 3 29   0
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis; physically and... Krr1p binding protein 2 67   0
ABF2 YMR072W Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and ... HMG-1 homolog 2 45   0
  YOL087C     2 21   0
SSN3 YPL042C Cyclin-dependent protein kinase, component of RNA polymerase II holoenzyme; invo... cyclin (SSN8)-dependent serine/threonine protein kinase 2 78   0
SRP72 YPL210C Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) ... signal recognition particle component 2 20   0.0037
NHP10 YDL002C Protein related to mammalian high mobility group proteins; likely component of t... HMG1-box containing protein 2 51   0.1557
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 2 25   0.0285
CBF2 YGR140W Essential kinetochore protein, component of the CBF3 multisubunit complex that b... centromere binding factor CBF3 110 kDa subunit 2 39   0.2006
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA ... DNA polymerase delta binding protein 2 73   0.2742
CDC19 YAL038W Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoeno... pyruvate kinase 2 54   0.1396
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that amin... tyrosine-tRNA ligase 2 21   0
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochon... heat shock protein 78 2 39   0
CIN5 YOR028C Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pl... bZIP (basic-leucine zipper) protein|can activate transcription from a promoter containing a Yap recognition site 2 15   0.0013
RAD59 YDL059C Protein involved in the repair of double-strand breaks in DNA during vegetative ... the RAD59 gene product has homology to the Rad52 protein 2 34   0.2262
  YBL009W     2 9   0
SIT4 YDL047W Type 2A-related serine-threonine phosphatase that functions in the G1/S transiti... similar to catalytic subunit of bovine type 2A protein phosphatase 2 79   0.0018
NOP2 YNL061W Probable RNA m(5)C methyltransferase, essential for processing and maturation of... 90 kDa protein homologous to a human proliferation-associated nucleolar protein, p120 2 124   0
MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit ribosomal protein S5 (putative) 2 59   0
RPP0 YLR340W Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; sh... ribosomal protein P0 (A0) (L10E) 2 124   0
MRPL16 YBL038W Mitochondrial ribosomal protein of the large subunit ribosomal protein 2 44   0
BOI1 YBL085W Protein implicated in polar growth, functionally redundant with Boi2p; interacts...   2 67   0
  YDL025C     2 49   0
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative reg... Glc7p regulatory subunit 2 34   0.2414
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 2 47 -1.6510 0
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase and is required ...   2 61   0.0047
SLX9 YGR081C Protein of unknown function; deletion mutant has synthetic fitness defect with a...   2 20   0.0005
SAK1 YER129W Upstream kinase for the SNF1 complex; partially redundant function with Elm1p an...   2 27   0.0001
TWF1 YGR080W Twinfilin, highly conserved actin monomer-sequestering protein involved in regul... twinfilin A, an actin monomer sequestering protein 2 11   0.0002
VCX1 YDL128W Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; ... vacuolar H+/Ca2+ exchanger 1 6   0
FAP7 YDL166C Essential NTPase required for small ribosome subunit synthesis, mediates process...   1 12   0

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