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SONAR Targetspace for GAMBOGIC ACID AMIDEZ-score WebGraph NB WebGraph
Targetspace hs 133 262
Targetspace hs pval0.201438848920860.81521739130435
XgmmL File for compound download download
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Targetspace Analysis download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition ... mannosyltransferase 4 49   0.0199
HLJ1 YMR161W Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p pro...   4 102   0
NPL4 YBR170C Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p ...   2 26   0.0051
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthes... Dol-P-Man dependent alpha(1-3) mannosyltransferase (putative) 2 42   0.0174
TIR3 YIL011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins... cell wall mannoprotein 2 3   0
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   2 30   0
STE24 YJR117W Highly conserved zinc metalloprotease that functions in two steps of a-factor ma... zinc metallo-protease 2 55   0.2163
HXT8 YJL214W Protein of unknown function with similarity to hexose transporter family members... hexose permease 2 13   0
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the dire... pyruvate dehydrogenase alpha subunit (E1 alpha) 2 10   0.1458
ATG8 YBL078C Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, a... similar to LC3, a microtubule-associated protein from rat 2 20   0
APL2 YKL135C Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; b... beta-adaptin|clathrin associated protein complex large subunit 2 19   0
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   2 10   0.0844
RVB2 YPL235W Essential protein involved in transcription regulation; component of chromatin r... transcriptional regulator 2 20   0.0031
SAP155 YFR040W Protein that forms a complex with the Sit4p protein phosphatase and is required ...   2 29   0
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   2 26   0.0001
ILM1 YJR118C Protein of unknown function; may be involved in mitochondrial DNA maintenance; r...   2 108   0.0101
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   2 25   0.0055
DFG16 YOR030W Probable multiple transmembrane protein, involved in invasive growth upon nitrog...   2 21   0.0005
ELF1 YKL160W Transcription elongation factor that contains a conserved zinc finger domain; im...   2 19   0
UBX4 YMR067C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 37   0.004
GOT1 YMR292W Evolutionarily conserved non-essential protein present in early Golgi cisternae ... membrane protein 2 34   0
  YMR073C     2 23   0.0015
HYM1 YKL189W Component of the RAM signaling network that is involved in regulation of Ace2p a...   2 24   0.0904
UPC2 YDR213W Sterol regulatory element binding protein, induces transcription of sterol trans... zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type 2 24   0
SPT2 YER161C Protein involved in negative regulation of transcription, exhibits regulated int... non-specific DNA binding protein 2 51   0
MUC1 YIR019C GPI-anchored cell surface glycoprotein required for diploid pseudohyphal formati... cell surface flocculin with structure similar to serine/threonine-rich GPI-anchored cell wall proteins 2 46   0.0559
MSB1 YOR188W Protein involved in positive regulation of both 1,3-beta-glucan synthesis and th...   2 11   0.1078
PXL1 YKR090W LIM domain-containing protein that localizes to sites of polarized growth, requi...   2 4   0.1236
SEL1 YML013W UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 86   0.2689
USA1 YML029W Protein that interacts in the two-hybrid system with the U1 snRNP-specific prote... pre-mRNA splicing factor (putative) 2 39   0
SPC2 YML055W Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyz... signal peptidase complex subunit|similar to mammalian protein SPC25 2 45   0
MDM38 YOL027C Mitochondrial inner membrane protein, required for K+/H+ exchange and for normal...   1 8   0.0001
RRP6 YOR001W Exonuclease component of the nuclear exosome; contributes to the quality-control...   1 61   0.0746
THP1 YOL072W Nuclear pore-associated protein, forms a complex with Sac3p that is involved in ...   1 35   0
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of th... TFIIF interacting component of CTD phosphatase 1 25   0.2497
PMD1 YER132C Protein with an N-terminal kelch-like domain, putative negative regulator of ear...   1 3   0.0205
NRD1 YNL251C RNA-binding protein that interacts with the C-terminal domain of the RNA polymer...   1 11   0
UBP2 YOR124C Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, ... ubiquitin-specific protease 1 7   0
RVB1 YDR190C Essential protein involved in transcription regulation; component of chromatin r...   1 13   0.0232
CET1 YPL228W Beta (RNA 5--triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (... RNA 5--triphosphatase|mRNA capping enzyme beta subunit (80 kDa) 1 8   0.0002

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