Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for IRIGENOLZ-score WebGraph NB WebGraph
Targetspace hs 297 344
Targetspace hs pval0.0867678958785250.35040431266846
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polyme...   8 128   0.0021
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 7 62   0.1544
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   7 47   0.0205
CDC5 YMR001C Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bu... protein kinase 7 109   0.0299
SIN3 YOL004W DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in tran... DNA binding protein|involved in transcriptional regulation 6 75   0
SDS3 YIL084C Component of the Rpd3p/Sin3p deacetylase complex required for its structural int...   6 33   0.0277
RXT2 YBR095C Protein possibly involved in cell fusion and invasive growth   6 33   0.0114
UME1 YPL139C Negative regulator of meiosis, required for repression of a subset of meiotic ge... transcriptional modulator 6 39   0.005
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA ... DNA polymerase delta binding protein 6 73   0.024
CDC34 YDR054C Ubiquitin-conjugating enzyme or E2; together with Skp1p, Rbx1p, Cdc53p, and an F... ubiquitin-conjugating enzyme 6 42   0.0025
ERV41 YML067C Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involve...   6 15   0
BRE1 YDL074C E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, r...   6 27 -5.6734 0
SAP30 YMR263W Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is in...   5 32 -10.4519 0.1879
CNA1 YLR433C Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calci... calcineurin subunit A 5 27   0.079
PHO23 YNL097C Probable component of the Rpd3 histone deacetylase complex, involved in transcri...   5 36   0.1199
RXT3 YDL076C Protein of unknown function, may be involved in chromatin silencing   5 27   0.0003
CLA4 YNL298W Cdc42p activated signal transducing kinase of the PAK (p21-activated kinase) fam... Ste20p homolog|protein kinase 5 68 -1.1183 0
CMD1 YBR109C Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mito... calmodulin 5 122   0
PIL1 YGR086C Integral membrane protein that along with Lsp1p is a primary component of eisoso...   5 80   0
TPD3 YAL016W Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also co... protein phosphatase 2A regulatory subunit A 5 49   0
BAS1 YKR099W Myb-related transcription factor involved in regulating basal and induced expres... transcription factor 5 11   0.0037
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   5 51 -1.7299 0.0027
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex, which is involved in regulati...   5 57 -12.0062 0
NOT3 YIL038C Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... CCR4 transcriptional complex component 4 31   0.1981
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 4 143 -6.8965 0
LEO1 YOR123C Component of the Paf1 complex, which associates with RNA polymerase II and is in...   4 38   0
HSL7 YBR133C Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bu... Has homology to arginine methyltransferases 4 16   0.0006
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   4 98 -2.3752 0
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP, plays an essential role in pre-mRNA ... 17 kDa U4/U6.U5 associated protein 4 45   0
POL30 YBR088C Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DN... Proliferating Cell Nuclear Antigen (PCNA) 4 61   0.0001
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis... cyclophilin|peptidyl-prolyl cis-trans isomerase (PPIase) 4 52   0
DEP1 YAL013W Transcriptional modulator involved in regulation of structural phospholipid bios...   4 26 -9.2390 0.0009
CAF40 YNL288W Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling...   4 39   0.1772
ASH1 YKL185W Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in t...   4 42   0
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response; functions as part ... Ser/Thr Kinase 4 123   0.0006
CAF130 YGR134W Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex...   4 23   0

Service provided by the Mike Tyers Laboratory