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SONAR Targetspace for ERGOSTEROLZ-score WebGraph NB WebGraph
Targetspace hs 109 102
Targetspace hs pval0.391666666666670.35405405405405
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score⇑ hyperg
ACO1 YLR304C Aconitase, required for the tricarboxylic acid (TCA) cycle and also independentl... aconitase 2 28   0
CBF2 YGR140W Essential kinetochore protein, component of the CBF3 multisubunit complex that b... centromere binding factor CBF3 110 kDa subunit 2 39   0.2006
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   2 5   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   3 45   0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   2 31   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 6 25   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 6 13   0
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochon... heat shock protein 78 2 39   0
ITR1 YDR497C Myo-inositol transporter with strong similarity to the minor myo-inositol transp... myo-inositol transporter 2 6   0.0008
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 4 13   0
MIG1 YGL035C Transcription factor involved in glucose repression; C2H2 zinc finger protein si... C2H2 zinc finger protein that resembles the mammalian Egr and Wilms tumour proteins 2 33   0.1991
MPS1 YDL028C Dual-specificity kinase required for spindle pole body (SPB) duplication and spi...   2 70   0.2734
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 3 22   0.0025
MSB4 YOL112W GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, l...   3 11   0
NGG1 YDR176W Transcriptional regulator involved in glucose repression of Gal4p-regulated gene... genetic and mutant analyses suggest that Ngg1p (Ada3p) is part of two transcriptional adaptor/HAT (histone acetyltransferase complexes, the 0.8 MD ADA complex and the 1.8 MD SAGA complex|transcription factor 2 65   0.0707
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evoluti... pyruvate dehydrogenase beta subunit (E1 beta) 3 31   0.0623
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 2 25   0.0285
RGT1 YKL038W Glucose-responsive transcription factor that regulates expression of several glu... transcriptional activator|transcriptional repressor 2 18   0
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mamma... protein phosphatase 2A (PP2A) B-type regulatory subunit 2 24   0.0003
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   3 8   0.2273
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases with similarity to ...   2 57   0
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex, involved in proper assem... histone acetyltransferase SAGA complex member|transcription factor 2 70   0.2555
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tran...   2 84   0.0423
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiati... TATA-binding protein-associated-factor 2 102   0.0001
TAP42 YMR028W Essential protein involved in the TOR signaling pathway; physically associates w... 42 kDa protein that physically associates with the PP2A and SIT4 protein phosphatase catalytic subunits 2 23   0
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions ubiquitin carboxyl-terminal hydrolase 1 19   0
VPH2 YKL119C Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, a... 25.2 kDa protein involved in assembly of vacuolar H(+) ATPase 2 8   0
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   2 12   0.0322
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 3 18   0.0632
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   2 22   0
YIF1 YNL263C Integral membrane protein required for the fusion of ER-derived COPII transport ...   3 39   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 28   0.0657
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   4 43   0
YIP4 YGL198W Protein that interacts with Rab GTPases; computational analysis of large-scale p...   3 26   0
YOP1 YPR028W Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpr...   3 17   0
ZDS2 YML109W Protein that interacts with silencing proteins at the telomere, involved in tran...   2 47   0.0002
DRS2 YAL026C Integral membrane Ca(2+)-ATPase involved in aminophospholipid translocation; req... P-type ATPase, potential aminophospholipid translocase 2 29 -6.2034 0.2288
UBP8 YMR223W Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyl...   2 49 -2.4508 0.241
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transc... transcriptional regulator 2 76 -2.0365 0.2494
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network; forms heterod...   3 14 -1.8558 0

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