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SONAR Targetspace for ERGOSTEROLZ-score WebGraph NB WebGraph
Targetspace hs 109 102
Targetspace hs pval0.391666666666670.35405405405405
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 5 56   0.0001
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   5 32   0
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
RSN1 YMR266W Membrane protein of unknown function; overexpression suppresses NaCl sensitivity...   3 10   0.1388
SED5 YLR026C cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and t... syntaxin family 3 20   0.0017
  YDR266C     3 6   0
INO4 YOL108C Transcription factor required for derepression of inositol-choline-regulated gen... basic helix-loop-helix (bHLH) protein 3 10   0
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 3 15   0
STV1 YMR054W Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv... 110 kDa subunit; not in vacuole membrane|vacuolar H-ATPase 3 10   0
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 3 33   0.2144
  YPR084W     3 4   0.0001
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 3 21   0.0221
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 9   0.1012
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 22   0.0657
COG1 YGL223C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   3 26   0.0204
ATG20 YDL113C Protein required for transport of aminopeptidase I (Lap4p) through the cytoplasm... PX domain-containing protein that binds Apg17 and Cvt13, and is required for import of precursor Ape1. 3 6   0
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 3 10   0.0001
NUP2 YLR335W Protein involved in nucleocytoplasmic transport, binds to either the nucleoplasm... nucleoporin 3 27   0
GAP1 YKR039W General amino acid permease; localization to the plasma membrane is regulated by... general amino acid permease 3 41   0
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   2 8   0.0711
  YDR107C     2 5   0.0175
HXK1 YFR053C Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of gl... hexokinase I (PI) (also called hexokinase A) 2 6   0.2553
  ETG9627     2 5   0
TLG1 YDR468C Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion ... tSNARE that affects a late Golgi compartment 2 6   0.0438
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   2 3   0.034
SWA2 YDR320C Auxilin-like protein involved in vesicular transport; clathrin-binding protein r... auxilin-like protein 2 24   0
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   2 10   0.0844
MAF1 YDR005C Negative regulator of RNA polymerase III; component of several signaling pathway...   2 50   0.1925
TOA1 YOR194C TFIIA large subunit; involved in transcriptional activation, acts as antirepress... transcription factor IIA subunit alpha 2 9   0
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   2 8   0
TOA2 YKL058W TFIIA small subunit; involved in transcriptional activation, acts as antirepress... beta|transcription factor IIA subunit 2 11   0
GLK1 YCL040W Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irrever... glucokinase 2 6   0.2679
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 2 15   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   2 73   0.0004
RVB2 YPL235W Essential protein involved in transcription regulation; component of chromatin r... transcriptional regulator 2 20   0.0031
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 2 20   0.0145
TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNAR... integral membrane protein 2 3   0
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   2 5   0
  YEL043W     2 4   0

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