Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
LST8 YNL006W Protein required for the transport of amino acid permease Gap1p from the Golgi t...   6 38   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 16   0
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   6 48   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
SCH9 YHR205W Protein kinase that regulates signal transduction activity and G1 progression, c... cAMP-dependent protein kinase homolog|suppressor of cdc25ts 5 25   0
NPR1 YNL183C Protein kinase that stabilizes several plasma membrane amino acid transporters b... protein kinase homolog 5 39 -5.4710 0
CRM1 YGR218W Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits ... chromosome region maintenance protein 5 111   0
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates g...   4 31   0.0493
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-I), regulates the RAS/cAMP pathway v... chromatin assembly factor-I (CAF-I) p50 subunit|negative regulator of ras-mediated cAMP induction|similar to GTP-binding protein beta subunit 4 15   0.1016
HOT1 YMR172W Transcription factor required for the transient induction of glycerol biosynthet... nuclear protein 4 16   0
SPT4 YGR063C Protein that forms a complex with Spt5p and mediates both activation and inhibit... transcriptional regulator|zinc finger protein 3 37   0.0103
CDC45 YLR103C DNA replication initiation factor; recruited to MCM pre-RC complexes at replicat... chromosomal DNA replication initiation protein 3 35   0.1509
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to ... subunit of the GINS complex 3 17   0
GLN3 YER040W Transcriptional activator of genes regulated by nitrogen catabolite repression (... transcriptional activator of nitrogen-regulated genes 3 20   0.003
  YGR058W     3 12   0.0001
RPL42A YNL162W Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and... ribosomal protein L42A (YL27) (L41A) 3 12   0
STE50 YCL032W Protein involved in mating response, invasive/filamentous growth, and osmotolera... contains SAM (sterile alpha motif) 3 32   0
VID21 YDR359C Component of the NuA4 histone acetyltransferase complex   3 39   0
STE7 YDL159W Signal transducing MAP kinase kinase involved in pheromone response, where it ph... MAP kinase kinase (MEK) 3 29   0
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 3 15   0.0005
CDC7 YDL017W DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and re... Cdc7p-Dbf4p kinase complex catalytic subunit 3 53   0.0853
YAR1 YPL239W Cytoplasmic ankyrin-repeat containing protein of unknown function, proposed to l... 200-amino-acid protein with two ANK repeat motifs and an acidic C terminus rich in PEST-like sequences 2 5   0
RIB2 YOL066C DRAP deaminase, catalyzes the third step of the riboflavin biosynthesis pathway;... DRAP deaminase|pseudouridine synthase 2 5   0
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 2 6   0.1783
SIC1 YLR079W Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, pre...   2 45   0
SNQ2 YDR011W ABC transporter protein involved in multidrug resistance and resistance to singl... ABC transporter 2 7   0
ENA1 YDR040C P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt toleranc... P-type ATPase Na+ pump|plasma membrane ATPase 2 3   0.0004
ENA2 YDR039C P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likel... P-type ATPase Na+ pump|plasma membrane ATPase|plasma membrane protein 2 5   0
ENA5 YDR038C Protein with similarity to P-type ATPase sodium pumps Na+ ATPase 2 6   0
  YAR010C     2 20   0
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   2 11   0.0055
DST1 YGL043W General transcription elongation factor TFIIS, enables RNA polymerase II to read... RNA polymerase II elongation factor|Transcription elongation factor S-II (TFIIS)|transcription elongation factor 2 38   0.0331
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required f... DNA polymerase epsilon subunit B 2 53   0
DNF2 YDR093W Non-essential P-type ATPase that is a potential aminophospholipid translocase, l... Potential aminophospholipid translocase 2 7   0
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 2 58   0.1778
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes; implicated in secreti...   2 26   0.1407
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 2 13   0
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 2 38   0

Service provided by the Mike Tyers Laboratory