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SONAR Targetspace for GAMBOGIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 128 0
Targetspace hs pval0.0891304347826091
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
LEO1 YOR123C Component of the Paf1 complex, which associates with RNA polymerase II and is in...   5 38   0
CKA2 YOR061W Alpha- catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles... protein kinase CK2 alpha- subunit 5 128 -7.7708 0
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polyme...   5 128   0.0648
CTR9 YOL145C Component of the Paf1p complex, which is a large complex that binds to and modul...   4 49   0.2039
CNA1 YLR433C Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calci... calcineurin subunit A 4 27   0.1534
CDC19 YAL038W Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoeno... pyruvate kinase 4 54   0.2074
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 4 143 -5.3467 0
CDC73 YLR418C Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rt...   4 61 -12.9403 0
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex; associates with core polymera... RNA polymerase II holoenzyme/mediator subunit 4 84   0.1492
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   4 51 -10.7832 0.0153
RTF1 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly... nuclear protein 4 36   0.0552
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA ... DNA polymerase delta binding protein 4 73   0.131
CKB1 YGL019W Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles ... protein kinase CK2 beta subunit 4 83   0.0488
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evoluti... pyruvate dehydrogenase beta subunit (E1 beta) 3 31   0.0623
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tra... TFIID subunit 3 82   0.0018
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); i... adenylate cyclase regulatory protein 3 65   0.1569
SML1 YML058W Ribonucleotide reductase inhibitor involved in regulating dNTP production; regul...   3 45   0.2253
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II t... TFIID subunit 3 97   0.1553
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 3 25   0.0025
ARF1 YDL192W ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of... ADP-ribosylation factor 3 51 -4.8002 0
RNR1 YER070W Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catal... ribonucleotide reductase, large (R1) subunit 3 20   0.0009
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the dire... pyruvate dehydrogenase alpha subunit (E1 alpha) 3 23   0.2035
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid, has similarity to ... lipoic acid synthase 3 13   0
STM1 YLR150W Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts wit... purine motif triplex-binding protein 3 133   0.0484
ABF2 YMR072W Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and ... HMG-1 homolog 3 45   0
VAM3 YOR106W Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in... syntaxin family 3 40 -10.2427 0
TAF1 YGR274C TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation,...   2 77   0.2186
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex, involved in proper assem... histone acetyltransferase SAGA complex member|transcription factor 2 70   0.2555
  YKL047W     2 5   0
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that amin... tyrosine-tRNA ligase 2 21   0
RNR3 YIL066C Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catal... ribonucleotide reductase, large (R1) subunit 2 17 -11.7652 0.0001
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tran...   2 84   0.0423
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 2 62   0.0073
SGF73 YGL066W Probable 73 kDa subunit of SAGA histone acetyltransferase complex Probable 73KkDa Subunit of SAGA histone acetyltransferase complex 2 57   0.2816
NSR1 YGR159C Nucleolar protein that binds nuclear localization sequences, required for pre-rR... nuclear localization sequence binding protein 2 44   0
NGG1 YDR176W Transcriptional regulator involved in glucose repression of Gal4p-regulated gene... genetic and mutant analyses suggest that Ngg1p (Ada3p) is part of two transcriptional adaptor/HAT (histone acetyltransferase complexes, the 0.8 MD ADA complex and the 1.8 MD SAGA complex|transcription factor 2 65   0.0707

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