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SONAR Targetspace for GAMBOGIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 128 0
Targetspace hs pval0.0891304347826091
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation, methylates ...   7 133 -1.1502 0
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition ... mannosyltransferase 6 49   0.0006
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 5 115   0.1357
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... ADP-ribosylation factor GTPase-activating protein (ARF GAP) 4 95   0
GOT1 YMR292W Evolutionarily conserved non-essential protein present in early Golgi cisternae ... membrane protein 4 34   0
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 4 108 -5.7476 0
IKI3 YLR384C Subunit of RNA polymerase II elongator histone acetyltransferase complex, involv...   4 80 -0.5565 0
LSM6 YDR378C Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either L... snRNP protein 4 41   0.166
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   4 57   0
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, ... mannosyltransferase complex component 4 31   0
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer t...   4 119 -3.7112 0
PRE9 YGR135W 20S proteasome beta-type subunit; the only nonessential 20S subunit proteasome component Y13 4 78 -4.3648 0
RPA49 YNL248C RNA polymerase I subunit A49 RNA polymerase A 49 kDa alpha subunit 3 44 -0.8460 0.2124
GOS1 YHL031C v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GO...   3 56   0
SAC1 YKL212W Lipid phosphoinositide phosphatase of the ER and Golgi, involved in protein traf... phosphoinositide phosphatase 3 64   0
GSG1 YDR108W Subunit of TRAPP (transport protein particle), a multi-subunit complex involved ...   3 97   0
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   3 62   0
DST1 YGL043W General transcription elongation factor TFIIS, enables RNA polymerase II to read... RNA polymerase II elongation factor|Transcription elongation factor S-II (TFIIS)|transcription elongation factor 3 111   0.0761
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn... galactosyltransferase 3 63   0
THP1 YOL072W Nuclear pore-associated protein, forms a complex with Sac3p that is involved in ...   3 35   0
UBP3 YER151C Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde... ubiquitin-specific protease 3 99   0
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   3 65   0.0023
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on... compass (complex proteins associated with Set1p) component 3 74   0.2273
VAN1 YML115C Component of the mannan polymerase I; forms a complex with Mnn9p, which is invol... mannosyltransferase 3 23   0.0874
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 3 28   0
DOC1 YGL240W Processivity factor required for the ubiquitination activity of the anaphase pro...   3 36 -1.1879 0.0526
ERG11 YHR007C Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol ... cytochrome P450 lanosterol 14a-demethylase 3 79   0.0039
APL2 YKL135C Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; b... beta-adaptin|clathrin associated protein complex large subunit 3 19   0
RRP6 YOR001W Exonuclease component of the nuclear exosome; contributes to the quality-control...   3 61 -2.9807 0.2111
SBE2 YDR351W Protein involved in the transport of cell wall components from the Golgi to the ...   3 7   0.0025
ARC18 YLR370C Subunit of the ARP2/3 complex, which is required for the motility and integrity ...   3 81 -0.7263 0.0534
LEA1 YPL213W Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically int...   3 31   0.0001
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interact... histone acetyltransferase SAGA complex member|transcription factor 3 119 -12.8663 0
UBP8 YMR223W Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyl...   3 97 -6.0665 0.2398
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   3 26   0.0003
HOS2 YGL194C Histone deacetylase required for gene activation via specific deacetylation of l...   3 74   0

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