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SONAR Targetspace for 5alpha-ANDROSTAN-3,17-DIONEZ-score WebGraph NB WebGraph
Targetspace hs 361 217
Targetspace hs pval0.0569620253164560.14645308924485
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   10 48   0
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 9 67 -2.9922 0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   9 32   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 12   0.0002
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   8 25   0.0526
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   7 21   0.0218
VPS29 YHR012W Endosomal protein that is a subunit of the membrane-associated retromer complex ...   7 52   0.0068
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 7 56   0.0014
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 6 20   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   6 30   0.1691
NHX1 YDR456W Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; req... Na+/H+ exchanger 6 61   0
PEP8 YJL053W Vacuolar protein sorting protein that forms part of the multimeric membrane-asso... vacuolar protein similar to mouse gene H<beta>58 6 27   0
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent prot... high affinity cAMP phosphodiesterase 6 62   0.054
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 6 28   0
SRO9 YCL037C Cytoplasmic RNA-binding protein that associates with translating ribosomes; invo...   6 30   0.0689
HKR1 YDR420W Serine/threonine rich cell surface protein that contains an EF hand motif; invol... contains EF hand motif|type I transmembrane protein 5 25   0
MTL1 YGR023W Protein with both structural and functional similarity to Mid2p, which is a plas... acts in concert with Mid2p to transduce cell wall stress signals 5 11   0
MID1 YNL291C N-glycosylated integral membrane protein of the ER membrane and plasma membrane,... N-glycosylated integral plasma membrane protein 5 28   0.1657
VAM7 YGL212W Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-... heptad repeat motif|hydrophilic protein 5 17   0.1676
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 5 33   0.1741
POG1 YIL122W Putative transcriptional activator that promotes recovery from pheromone induced... transcription factor (putative) 5 7   0
  ETG9627     5 5   0
YPK2 YMR104C Protein kinase with similarityto serine/threonine protein kinase Ypk1p; function... protein kinase 5 12   0
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubi...   5 31   0.0027
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   5 41   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 5 19   0.0837
SWA2 YDR320C Auxilin-like protein involved in vesicular transport; clathrin-binding protein r... auxilin-like protein 5 24   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   5 20   0.1088
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 4 10   0
TLG1 YDR468C Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion ... tSNARE that affects a late Golgi compartment 4 6   0.0004
  YDR266C     4 6   0
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   4 8   0.1764
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   4 7   0.0968
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 4 9   0.0319
  YEL043W     4 4   0
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane, responsible for the major...   4 7   0.1534
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 4 20   0.0751
SNF4 YGL115W Protein kinase activator found in a complex containing Snf1p and members of the ... associates with Snf1p 4 31   0
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 4 11   0
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 4 33   0.121

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