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SONAR Targetspace for 5alpha-ANDROSTAN-3,17-DIONEZ-score WebGraph NB WebGraph
Targetspace hs 361 217
Targetspace hs pval0.0569620253164560.14645308924485
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:34
Sym Orf Description Function No All Z_score hyperg
VAM10 YOR068C Protein involved in vacuole morphogenesis; acts at an early step of homotypic va... Required for normal tethering of vacuoles prior to fusion. 17 144   0
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 13 147   0
FAR11 YNL127W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   12 104   0.0004
IRS4 YKR019C Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentr...   11 112   0.0008
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 11 80   0
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapam... peptidyl-prolyl cis-trans isomerase (PPIase) 11 131   0
MYO3 YKL129C One of two type I myosins; localizes to actin cortical patches; deletion of MYO3... myosin I 11 67   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   10 134   0.0975
MET6 YER091C Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; ... 5-methyltetrahydropteroyl triglutamate homocysteine methyltransferase|N5-methyltetrahydrofolate homocysteine methyltransferase|vitamin B12-(cobalamin)-independent methionine synthase 10 88   0
ECM8 YBR076W Non-essential protein of unknown function   10 50   0.0014
BIO2 YGR286C Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is th... biotin synthase 10 30   0
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   9 109   0.0256
RNH70 YGR276C 3- exoribonuclease, required for 5S and tRNA-Arg3 maturation ribonuclease H 9 79   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   9 100   0
ERV46 YAL042W Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involve... ER-Golgi transport vesicle protein 9 83   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   9 94   NAN
CAF40 YNL288W Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling...   9 105   0.0422
MSB3 YNL293W GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exo... GTPase activating protein (GAP) for Ypt6 9 58   0
  YOR246C     8 92   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   8 79   0.0842
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3, which is involved...   8 97   0
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 8 98   0
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   8 55   0.1234
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing, interacts with Si...   8 51   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   8 48   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   8 89   0
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   8 112   0.0791
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase and is required ...   8 126   0
EDC1 YGL222C RNA-binding protein, activates mRNA decapping directly by binding to the mRNA su...   8 28   0.0003
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 8 46   0
HKR1 YDR420W Serine/threonine rich cell surface protein that contains an EF hand motif; invol... contains EF hand motif|type I transmembrane protein 8 77   0
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component ... ubiquinol cytochrome C oxidoreductase subunit 6 (17 kDa) 8 60   0
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 8 34   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 8 107   0

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