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SONAR Targetspace for 5alpha-ANDROSTAN-3beta,17beta-Z-score WebGraph NB WebGraph
Targetspace hs 316 0
Targetspace hs pval0.0121212121212121
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 12   0.0002
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   6 42   0
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic; regulates potassiu... ADP-ribosylation factor-like protein 1 6 141   0
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 6 56   0.0005
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   6 32   0
MAF1 YDR005C Negative regulator of RNA polymerase III; component of several signaling pathway...   5 50   0.003
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   5 25   0.1879
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 5 33   0.0534
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 4 20   0.0751
  YDR266C     4 6   0
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts p... phosphatidylserine decarboxylase 4 45   0.1079
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 4 65 -0.5221 0.0185
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   4 16   0
  YMR010W     4 4   0
RCE1 YMR274C Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras a... protease 4 14   0.2124
RSN1 YMR266W Membrane protein of unknown function; overexpression suppresses NaCl sensitivity...   4 10   0.0533
RPL16B YNL069C N-terminally acetylated protein component of the large (60S) ribosomal subunit, ... ribosomal protein L16B (L21B) (rp23) (YL15) 4 14   0.2102
STV1 YMR054W Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv... 110 kDa subunit; not in vacuole membrane|vacuolar H-ATPase 4 10   0
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 4 9   0
EMP70 YLR083C Protein whose 24kDa cleavage product is found in endosome-enriched membrane frac...   4 7   0.1508
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   4 8   0
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 4 19   0
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane, responsible for the major...   4 7   0.1534
  YIL039W     4 65   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   4 20   0.0683
  YDR107C     4 5   0.0845
RPL35A YDL191W Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and... ribosomal protein L35A 4 13   0.1574
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   4 5   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   4 73   0.0061
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   4 4   0.1123
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 4 10   0
IRS4 YKR019C Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentr...   4 10   0.2056
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 4 15   0
GEF1 YJR040W Chloride channel localized to late- or post-Golgi vesicles, involved in iron met... transport protein involved in intracellular iron metabolism (putative) 4 10   0
TEF4 YKL081W Translation elongation factor EF-1 gamma translation elongation factor EF-1gamma 4 15   0.2064
BST1 YFL025C GPI inositol deacylase of the ER that negatively regulates COPII vesicle formati...   4 41   0
SRO7 YPR032W Protein with roles in exocytosis and cation homeostasis; functions in docking an... yeast homolog of the Drosophila tumor suppressor, lethal giant larvae 4 34   0.0197
  ETG9627     4 5   0
  YEL043W     4 4   0
PRP4 YPR178W Splicing factor, component of the U4/U6-U5 snRNP complex associates with the U4/U6 snRNP 4 22   0

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