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SONAR Targetspace for ICHTHYNONEZ-score WebGraph NB WebGraph
Targetspace hs 377 309
Targetspace hs pval0.105960264900660.80215827338129
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 7 81 -2.0726 0
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   6 21   0.0534
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   6 48   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   5 16   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   5 30   0.1876
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   5 32   0
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic; regulates potassiu... ADP-ribosylation factor-like protein 1 4 141   0
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 4 20   0.0043
  ETG9627     4 5   0
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   4 25   0.1995
  YPR084W     4 4   0.0003
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 4 19   0
PEP8 YJL053W Vacuolar protein sorting protein that forms part of the multimeric membrane-asso... vacuolar protein similar to mouse gene H<beta>58 4 27   0
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 3 56   0
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 3 20   0.0384
BST1 YFL025C GPI inositol deacylase of the ER that negatively regulates COPII vesicle formati...   3 41   0
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
RAD4 YER162C Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide ex...   3 17   0.0823
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   3 20   0.034
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 3 9   0
OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kina...   3 22   0.0133
NEM1 YHR004C Protein of the nuclear envelope required for the spherical shape of the nucleus;...   3 66   0.0008
  YIL039W     3 65   0
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 3 10   0
  YEL043W     3 4   0
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 3 76   0
SNF4 YGL115W Protein kinase activator found in a complex containing Snf1p and members of the ... associates with Snf1p 3 31   0
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane, responsible for the major...   3 7   0.232
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   3 7   0.0535
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 3 9   0.1012
FUN30 YAL019W Protein whose overexpression affects chromosome stability, potential Cdc28p subs...   3 27   0
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   3 8   0
BRE2 YLR015W Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 ... compass (complex proteins associated with Set1p) component 3 61   0.2302
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   3 42 -4.9437 0
RCE1 YMR274C Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras a... protease 3 14   0.2087
TLG2 YOL018C Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fus... tSNARE that affects a late Golgi compartment 3 128   0
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   3 41   0
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 3 15   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   3 73   0.0019

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