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SONAR Targetspace for PERIPLOCYMARINZ-score WebGraph NB WebGraph
Targetspace hs 330 110
Targetspace hs pval0.0503144654088050.26196473551637
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition ... mannosyltransferase 4 49   0.0199
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 4 76   0
HLJ1 YMR161W Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p pro...   4 102   0
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   4 30   0
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by bot... glycerol-3-phosphate dehydrogenase 4 10   0
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   3 26   0.0003
SNT1 YCR033W Subunit of the Set3C deacetylase complex; putative DNA-binding protein   3 47   0
HST1 YOL068C NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p...   2 25   0
NDI1 YML120C NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in t... NADH:ubiquinone oxidoreductase|Type II NAD(P)H:quinone oxidoreductase 2 4   0
AAT1 YKL106W Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloaceta... aspartate aminotransferase 2 10   0
KIN3 YAR018C Nonessential protein kinase with unknown cellular role protein kinase 2 28   0
HST2 YPL015C Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD...   2 24   0
MDH2 YOL126C Cytoplasmic malate dehydrogenase, one of the three isozymes that catalyze interc... malate dehydrogenase 2 4   0.212
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); i... adenylate cyclase regulatory protein 2 36   0.277
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... NAD-dependent isocitrate dehydrogenase 2 15 -0.8448 0.0077
ACP1 YKL192C Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate... acyl carrier protein 2 4   0
HAP4 YKL109W Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding co... transcriptional activator protein of CYC1 (component of HAP2/HAP3 heteromer) 2 10   0.1079
CYT1 YOR065W Cytochrome c1, component of the mitochondrial respiratory chain; expression is r... cytochrome c1 2 16   0.2008
CIT2 YCR005C Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloaceta... citrate synthase 2 13   0
HIR3 YJR140C Transcriptional corepressor involved in the cell cycle-regulated transcription o...   2 17   0
ELF1 YKL160W Transcription elongation factor that contains a conserved zinc finger domain; im...   2 19   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   2 30   0.0653
PTK2 YJR059W Putative serine/threonine protein kinase involved in regulation of ion transport...   2 23   0.045
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved... GDP/GTP exchange factor 2 14   0.2404
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved... ARF GTP/GDP exchange factor 2 9   0.0882
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... ADP-ribosylation factor GTPase-activating protein (ARF GAP) 2 95   0
DOA4 YDR069C Ubiquitin hydrolase, required for recycling ubiquitin from proteasome-bound ubiq... ubiquitin isopeptidase 2 75   0.166
MEH1 YKR007W Component of the EGO complex, which is involved in the regulation of microautoph...   2 35   0.1251
SET3 YKR029C Defining member of the SET3 histone deacetylase complex which is a meiosis-speci...   2 90   0
YTA7 YGR270W Protein of unknown function, member of CDC48/PAS1/SEC18 family of ATPases, poten...   2 31   0
SAM1 YLR180W S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP...   2 11   0.2114
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the dire... pyruvate dehydrogenase alpha subunit (E1 alpha) 2 10   0.1458
SPT2 YER161C Protein involved in negative regulation of transcription, exhibits regulated int... non-specific DNA binding protein 2 51   0
  YMR073C     2 23   0.0015
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   2 97   0
OAC1 YKL120W Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and ... oxaloacetate transport protein 2 12   0
ATG8 YBL078C Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, a... similar to LC3, a microtubule-associated protein from rat 2 20   0
UBX4 YMR067C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 37   0.004
HXT8 YJL214W Protein of unknown function with similarity to hexose transporter family members... hexose permease 2 13   0
TIR3 YIL011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins... cell wall mannoprotein 2 3   0

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