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SONAR Targetspace for OBLIQUINZ-score WebGraph NB WebGraph
Targetspace hs 402 386
Targetspace hs pval0.0415800415800420.51818181818182
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 21 33   0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 18 143 -29.0153 NAN
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 15 38 -0.6292 0.0451
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 14 25 -18.4186 NAN
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 11 39   0
MYO3 YKL129C One of two type I myosins; localizes to actin cortical patches; deletion of MYO3... myosin I 11 54   0
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   10 33 -23.4980 0.0321
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   10 89   0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   10 15   0.0832
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -38.6826 0.14
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 9 21   0
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   9 98 -33.3840 0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 9 24 -1.7457 0
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   8 51 -4.0154 0
CIN8 YEL061C Kinesin motor protein involved in mitotic spindle assembly and chromosome segreg...   8 18 -33.9580 0
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   8 109   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 8 36   0.1127
YAK1 YJL141C Serine-threonine protein kinase that is part of a glucose-sensing system involve...   8 69   0
MYO5 YMR109W One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 d... myosin I 8 85   0
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts dow...   7 41   0
UTP22 YGR090W Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on comp...   7 145   0
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 7 41   0
SCS2 YER120W Integral ER membrane protein that regulates phospholipid metabolism via an inter...   7 25   0
CSM1 YCR086W Nucleolar protein that forms a complex with Lrs4p which binds Mam1p at kinetocho...   7 73   0.0042
  YBR225W     6 13   0
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosi... tRNA:m5C-methyltransferase 6 32   0
ADH4 YGL256W Alcohol dehydrogenase type IV, dimeric enzyme demonstrated to be zinc-dependent ... alcohol dehydrogenase isoenzyme IV 6 12   0
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acy... glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase 6 20   0
DUS1 YML080W Dihydrouridine synthase, member of a widespread family of conserved proteins inc... tRNA dihydrouridine synthase 6 5   0
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains...   6 23   0
GAL7 YBR018C Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UD... galactose-1-phosphate uridyl transferase 6 9   0
LSP1 YPL004C Integral membrane protein that along with Pil1p is a primary component of eisoso...   6 79   0
EGD2 YHR193C Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) in... GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog 6 33   0
PIL1 YGR086C Integral membrane protein that along with Lsp1p is a primary component of eisoso...   6 80   0
CTR9 YOL145C Component of the Paf1p complex, which is a large complex that binds to and modul...   6 49   0.1388
RTF1 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly... nuclear protein 6 36   0.1343

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