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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:33
Sym Orf Description Function No All Z_score hyperg
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 4 28   0.1407
STI1 YOR027W Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperone... heat shock protein also induced by canavanine and entry into stationary phase 4 46   0.063
CIN8 YEL061C Kinesin motor protein involved in mitotic spindle assembly and chromosome segreg...   4 18 -47.2698 0
CDC6 YJL194W Essential ATP-binding protein required for DNA replication, component of the pre... pre-initiation complex component 3 36   0
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesiz... GDP-mannose pyrophosphorylase|mannose-1-phosphate guanyltransferase 3 94   0
PEX11 YOL147C Peroxisomal membrane protein required for peroxisome proliferation and medium-ch... peroxin|peroxisomal membrane protein 3 12 -54.0720 0
CNS1 YBR155W TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and sti...   3 31   0
BUB1 YGR188C Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the ...   3 23   0
SUP35 YDR172W Translation termination factor eRF3; altered protein conformation creates the [P... translation termination factor eRF3 3 72   0
  YMR124W     3 19   0.0023
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 4|similar to human RFC 40 kDa subunit 3 34   0.0355
SGT1 YOR057W Probable cochaperone, regulates activity of Cyr1p (adenylyl cyclase); involved i...   3 27   0
GYL1 YMR192W Putative GTPase activating protein (GAP) that may have a role in polarized exocy...   3 18   0
NUP57 YGR119C Essential subunit of the nuclear pore complex (NPC), functions as the organizing... nucleoporin 2 49   0.267
HRD1 YOL013C Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradati...   2 63   0.2822
PEP12 YOR036W Target membrane receptor (t-SNARE) for vesicular intermediates traveling between... c-terminal TMD|integral membrane protein 2 32   0.0554
ECM2 YBR065C Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix I...   2 32   0
SBA1 YKL117W Co-chaperone that binds to and regulates Hsp90 family chaperones; important for ... HSP90 associated co-chaperone 2 33   0
RPL18A YOL120C Protein component of the large (60S) ribosomal subunit, identical to Rpl18Bp and... ribosomal protein L18A (rp28A) 2 77   0
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 3|similar to human RFC 36 kDa subunit 2 33   0.0014
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 2|similar to human RFC 37 kDa subunit 2 39   0.0104
HSP104 YLL026W Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refol... heat shock protein 104 2 58 -53.1858 0
SAN1 YDR143C Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of ab...   2 57   0.1028
RPB9 YGL070C RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription st... RNA polymerase II core subunit 2 45   0.1204
CAM1 YPL048W Translational cofactor elongation factor-1 gamma, participates in the regulation... calcium and phospholipid binding protein homologous to translation elongation factor 1-gamma (EF-1gamma) 2 25   0.1881
RLR1 YNL139C Subunit of the THO complex, which is required for efficient transcription elonga...   2 28   0.2417
BSP1 YPR171W Adapter that links synaptojanins Inp2p and Inp53p to the cortical actin cytoskel...   2 39   0.018
SPS1 YDR523C Putative protein serine/threonine kinase expressed at the end of meiosis and loc...   2 54   0
RTG2 YGL252C Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p...   2 34   0.087
NUP53 YMR153W Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or... karyopherin docking complex component of the nuclear pore complex|nuclear pore complex subunit 2 56   0
MAD2 YJL030W Component of the spindle-assembly checkpoint complex, which delays the onset of ... spindle checkpoint complex subunit 2 41   0
MAD1 YGL086W Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated ...   2 25 -52.8993 0
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during...   2 14   0

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