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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
RAD57 YDR004W Protein that stimulates strand exchange by stabilizing the binding of Rad51p to ... RecA homolog|interacts with Rad 55p by two-hybrid analysis|similar to DMC1, RAD51, and RAD55 2 115   0
RAD17 YOR368W Checkpoint protein, involved in the activation of the DNA damage and meiotic pac... 3--5-exonuclease (putative) 2 85   0
MUS81 YDR386W Helix-hairpin-helix protein, involved in DNA repair and replication fork stabili...   2 72   0
SCC2 YDR180W Putative protein kinase and subunit of cohesin loading factor (Scc2p-Scc4p), a c...   2 7   0
RAD24 YER173W Checkpoint protein, involved in the activation of the DNA damage and meiotic pac... cell cycle exonuclease (putative) 2 118   0
SMC3 YJL074C Subunit of the multiprotein cohesin complex required for sister chromatid cohesi... SMC chromosomal ATPase family member 2 13   0
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric...   2 71   0
SLX8 YER116C Protein containing a RING finger domain that forms a complex with Hex3p; mutant ...   2 121   0
  YBR094W     2 30   0
MMS4 YBR098W Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branche...   2 54   0
  YDR065W     1 7   0.1372
RTT107 YHR154W Protein that interacts with Mms22p and is implicated in Mms22-dependent DNA repa...   1 94   0
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive...   1 6   0.0713
IRR1 YIL026C Subunit of the cohesin complex, which is required for sister chromatid cohesion ... cohesin complex subunit 1 6   0
PET130 YJL023C Protein required for respiratory growth   1 5   0.3096
DPB11 YJL090C Essential BRCT repeat protein, required on the prereplicative complex at replica... DNA polymerase II complex 1 38   0.3797
TEL1 YBL088C Protein kinase, primarily involved in telomere length regulation; contributes to...   1 64   0.1552
POL30 YBR088C Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DN... Proliferating Cell Nuclear Antigen (PCNA) 1 78   0
YOR1 YGR281W Plasma membrane transporter of the ATP-binding cassette (ABC) family, mediates e... ABC transporter 1 8   0.3578
NUP84 YDL116W Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup12... nuclear pore complex subunit|similar to mammalian Nup107p 1 38   0
  YER087W     1 24   0.0958
VPS3 YDR495C Cytoplasmic protein required for the sorting and processing of soluble vacuolar ...   1 74   0.2932
PAT1 YCR077C Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also ...   1 73   0.0112
MCD1 YDL003W Essential protein required for sister chromatid cohesion in mitosis and meiosis;...   1 63   0.0573
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps2... ribosomal protein S21B (S26B) (YS25) 1 10   0.2107
SMC1 YFL008W Subunit of the multiprotein cohesin complex, essential protein involved in chrom... SMC chromosomal ATPase family member 1 17   0.3281
CHK1 YBR274W DNA damage checkpoint effector kinase, mediates mitotic cell cycle arrest via ph... protein kinase 1 39   0.1183
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the load...   1 1   0
RIF1 YBR275C Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p t... RAP1-interacting factor 1 21   0.0907
MGM101 YJR144W Protein involved in mitochondrial genome maintenance; component of the mitochond... mitochondrial nucleoid protein 1 14   0.0086
HIT1 YJR055W Protein of unknown function, required for growth at high temperature   1 11   0.2801
SIZ1 YDR409W SUMO ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related... chromatin protein; SUMO1/Smt3 ligase 1 40   0.3087
ECO1 YFR027W Acetyltransferase required for the establishment of sister chromatid cohesion du...   1 24   0.0293
HST4 YDR191W Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved alo...   1 37   0.0387
HPR1 YDR138W Subunit of THO/TREX complexes that couple transcription elongation with mitotic ...   1 75   0

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