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SONAR Targetspace for PTAEROXYLINZ-score WebGraph NB WebGraph
Targetspace hs 524 118
Targetspace hs pval0.0427083333333330.065957446808511
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:32
Sym Orf Description Function No All Z_score hyperg
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 14 126 -2.0042 0
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 13 108 -2.3968 0
IKI3 YLR384C Subunit of RNA polymerase II elongator histone acetyltransferase complex, involv...   13 80 -0.6001 NAN
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 13 104   0
  YKL037W     12 12   0.0001
SEC66 YBR171W Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with... glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex required for translocation of presecretory proteins 12 109 -2.2411 NAN
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 12 145 -6.7381 NAN
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   11 65   0.1333
ELP4 YPL101W Elongator protein, part of the HAP subcomplex of Elongator, which is a six-subun... RNA polymerase II Elongator protein subunit 11 80   0.0014
URM1 YIL008W Ubiquitin-like protein with only weak sequence similarity to ubiquitin; depends ... ubiquitin-like protein 11 56   0
  YKL161C     10 5   0.1116
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 10 28   0.0012
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   10 54   0
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   10 16   0.0029
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 10 46   0
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 10 16   0
RIM13 YMR154C Calpain-like protease involved in proteolytic activation of Ri0m101p in response... cysteine protease 9 23   0.0126
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   9 31 -2.3914 0.1429
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 9 115   0.0047
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 8 27   0
ERG11 YHR007C Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol ... cytochrome P450 lanosterol 14a-demethylase 8 79   0.1044
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   8 46   0.0003
VPS8 YAL002W Membrane-associated hydrophilic protein that interacts with the small GTPase, Vp... membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the RING finger Zn2+ binding motif 8 38   0.1471
UBP3 YER151C Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde... ubiquitin-specific protease 7 99   0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   7 64   0.0252
HOS2 YGL194C Histone deacetylase required for gene activation via specific deacetylation of l...   7 74   0
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   7 93 -6.4580 0.0041
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage, interacts...   7 25   0.1324
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   7 72   0.1668
MMS2 YGL087C Protein involved in error-free postreplication DNA repair; forms a heteromeric c...   7 42   0

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