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SONAR Targetspace for PRENYLETINZ-score WebGraph NB WebGraph
Targetspace hs 114 387
Targetspace hs pval0.176263219741480.084415584415584
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:30
Sym Orf Description Function No All Z_score hyperg
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 9 145 -15.3572 NAN
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 9 104   0
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 7 108 -2.2388 0
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 7 126 -3.1406 0
ARC18 YLR370C Subunit of the ARP2/3 complex, which is required for the motility and integrity ...   7 81 -3.3941 0.1632
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress pr... copper chaperone 6 129   0
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 6 111 -4.0429 0
BRE5 YNR051C Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that core...   6 121   0
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 6 99   NAN
RAD57 YDR004W Protein that stimulates strand exchange by stabilizing the binding of Rad51p to ... RecA homolog|interacts with Rad 55p by two-hybrid analysis|similar to DMC1, RAD51, and RAD55 6 115   0
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 6 76   0
ARC40 YBR234C Essential subunit of the ARP2/3 complex, which is required for the motility and ...   6 44   0
HLJ1 YMR161W Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p pro...   6 102   0
VPS3 YDR495C Cytoplasmic protein required for the sorting and processing of soluble vacuolar ...   5 74   0.0326
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active...   5 60   0.0964
KAR3 YPR141C Minus-end-directed microtubule motor that functions in mitosis and meiosis, loca... kinesin-like nuclear fusion protein 5 150 -1.1951 0
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   5 97   0
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer t...   5 119 -3.5283 0
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... function unknown 5 110   0.0639
HOC1 YJR075W Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit... mannosyltransferase (putative) 5 64 -1.1691 0.0001
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   5 71 -2.8941 0.0262
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 5 46   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 5 19   0.0837
  YBR094W     4 30   0
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric...   4 71   0.0009
HYS2 YJR006W DNA polymerase III (delta) subunit, essential for cell viability; involved in DN... DNA polymerase delta subunit 4 17   0.0008
  YMR073C     4 23   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   4 30   0.1709
MMS2 YGL087C Protein involved in error-free postreplication DNA repair; forms a heteromeric c...   4 42   0.0007
GTR1 YML121W Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cyc... small GTPase (putative) 4 57   0.0077

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