Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for CEDRELONEZ-score WebGraph NB WebGraph
Targetspace hs 97 0
Targetspace hs pval0.425925925925931
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 5 19   0.0837
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer t...   5 119 -4.2965 0
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 5 126 -6.6649 0
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 4 25   0.0435
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   4 71 -12.9665 0.0114
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 4 104   0
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 3 46   0
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes ...   3 34   0.239
SMY1 YKL079W Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-term... kinesin heavy chain homolog 3 29   0
IKI3 YLR384C Subunit of RNA polymerase II elongator histone acetyltransferase complex, involv...   3 80 -1.3190 0
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated co...   3 24   0.0913
  YER139C     3 18   0.0349
UPC2 YDR213W Sterol regulatory element binding protein, induces transcription of sterol trans... zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type 3 24   0
MSB1 YOR188W Protein involved in positive regulation of both 1,3-beta-glucan synthesis and th...   3 11   0.0221
HAL5 YJL165C Putative protein kinase; overexpression increases sodium and lithium tolerance, ...   3 49   0
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involv... GTP-binding protein|rho subfamily 2 26   0.1895
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 2 8   0.1783
RVB2 YPL235W Essential protein involved in transcription regulation; component of chromatin r... transcriptional regulator 2 20   0.0031
RGA1 YOR127W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... rho GTPase activating protein (GAP) 2 17   0.1639
PXL1 YKR090W LIM domain-containing protein that localizes to sites of polarized growth, requi...   2 4   0.1236
VMA22 YHR060W Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) fun...   2 17   0.0406
CUP5 YEL027W Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohex... 17 kDa|VO sector subunit|dicyclohexylcarbodiimide binding subunit|proteolipid|vacuolar ATP synthase proteolipid C|vacuolar ATPase V0 domain subunit c (dicyclohexylcarbodiimide binding subunit) (17 kDa) 2 14   0.0015
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 2 28   0.0104
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 2 26 -8.3965 0.001
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 2 89 -12.2521 0
CMK2 YOL016C Calmodulin-dependent protein kinase; may play a role in stress response, many CA... calmodulin-dependent protein kinase 2 5   0
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppre... type 2C protein phosphatase 2 4   0.0037
UBA4 YHR111W Protein that activates Urm1p before its conjugation to proteins (urmylation); on...   2 43   0.0208
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   2 10   0.0844
ELP3 YPL086C Histone acetyltransferase subunit of the Elongator complex, which is a component... RNA polymerase II Elongator subunit|histone acetyltransferase 2 137   0
LEA1 YPL213W Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically int...   2 31   0.004
NIP100 YPL174C Large subunit of the dynactin complex, which is involved in partitioning the mit... large subunit of dynactin complex (putative) 2 68   0
CSF1 YLR087C Protein required for fermentation at low temperature   2 37   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   2 54   0
SBE2 YDR351W Protein involved in the transport of cell wall components from the Golgi to the ...   2 7   0.0006
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence; interacts ...   2 44   0.1535
RIM13 YMR154C Calpain-like protease involved in proteolytic activation of Ri0m101p in response... cysteine protease 2 23   0
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   2 25   0.0055
SOY1 YBR194W Protein proposed to be associated with the nuclear pore complex   2 14   0.1243
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton o... rho GTPase activating protein (GAP) 2 22   0.2351

Service provided by the Mike Tyers Laboratory