Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   12 51   0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26   0.14
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 10 25   NAN
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 10 24   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 10 36   0.0391
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   10 15   0.0832
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 9 13   0
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 8 8   0
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spin... ubiquitin-like protein 8 37   0
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 7 45   0
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 6 38   0
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 16   0
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   6 48   0
PIL1 YGR086C Integral membrane protein that along with Lsp1p is a primary component of eisoso...   5 80   0
PDC6 YGR087C Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, d... pyruvate decarboxylase isozyme 5 9   0
EGD2 YHR193C Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) in... GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog 5 33   0
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 20   0
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerat... 6-phosphogluconate dehydrogenase 5 29   0
OYE2 YHR179W Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), ho... NAPDH dehydrogenase (old yellow enzyme), isoform 2 5 25   0
KIC1 YHR102W Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possi...   5 22   0
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid required for ... proteasome regulatory particle subunit 5 66   0.0222
ROM1 YGR070W GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal wit...   5 5   0
GAL7 YBR018C Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UD... galactose-1-phosphate uridyl transferase 5 9   0
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 5 41   0
PRS4 YBL068W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 6   0
SIC1 YLR079W Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, pre...   5 45   0
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 5 74   0
LYS12 YIL094C Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for t... homo-isocitrate dehydrogenase 5 51   0
USE1 YGL098W Essential SNARE protein localized to the ER, involved in retrograde traffic from...   5 19   0
  YFR038W     5 7   0.0188
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 10   0
EBS1 YDR206W Protein of unknown function, contains a putative RNA recognition motif, deletion...   5 16   0

Service provided by the Mike Tyers Laboratory