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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 13 28   0.0105
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   13 64   0.1284
CDC28 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternat... cyclin-dependent protein kinase 10 110   0.0665
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 10 46   0
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   10 31   0.1159
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 8 115   0.0137
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppre... type 2C protein phosphatase 8 4   0.1437
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 8 27   0
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 8 16   0
ERD1 YDR414C Predicted membrane protein required for the retention of lumenal endoplasmic ret...   8 83   0
MCM1 YMR043W Transcription factor involved in cell-type-specific transcription and pheromone ... contains the 56 amino-acid MADS (MCM1, AG, DEFAm SRF)-box motif within its DNA binding domain, plays a central role in the formation of both repressor and activator complexes|transcription factor 8 14   0
RRD1 YIL153W Activator of the phosphotyrosyl phosphatase activity of PP2A; regulates G1 phase...   7 24   0
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   7 65   0.0571
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 20   0
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 6 26   0
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates g...   6 16   0.0032
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   6 4   0
FUS3 YBL016W Mitogen-activated protein kinase involved in mating pheromone response; activate... CDC28/cdc2 related protein kinase 6 32   0
RPC10 YHR143W-A RNA polymerase subunit, found in RNA polymerase complexes I, II, and III RNA polymerase II subunit 5 15   0
GGA2 YHR108W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 5 20   0
NCP1 YHR042W NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated ... NADP-cytochrome P450 reductase 5 11   0
ERG7 YHR072W Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squal... 2,3-oxidosqualene-lanosterol cyclase 5 5   0
DIE2 YGR227W Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in th... glucosyltransferase 5 48   0.0043
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 16   0
GPI16 YHR188C Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase c... GPI transamidase component, human PIG-T homologue 5 3   0
SIS2 YKR072C Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion ...   5 50   0.1812
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of gluc... glucoseamine-6-phosphate synthase|glutamine_fructose-6-phosphate amidotransferase 5 6   0
  YKL161C     5 5   0.0912
MCD4 YKL165C Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multime...   5 6   0
PRP16 YKR086W RNA helicase in the DEAH-box family involved in the second catalytic step of spl... ATP-binding protein (putative) 5 13   0
  YKL037W     5 12   0.1349
GPI1 YGR216C Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidyli...   5 4   0
BNR1 YIL159W Formin, nucleates the formation of linear actin filaments, involved in cell proc...   5 40   0.0128
YUR1 YJL139C Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; loc... mannosyltransferase 5 29   0.1313
INO1 YJL153C Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and ... L-myo-inositol-1-phosphate synthase 5 7   0
ACT1 YFL039C Actin, structural protein involved in cell polarization, endocytosis, and other ... actin 5 77   0.0504

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