Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:33
Sym Orf Description Function No All Z_score hyperg
TLG2 YOL018C Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fus... tSNARE that affects a late Golgi compartment 12 128   0
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   9 42   0
  YBR094W     9 30   0.0054
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   9 41   0
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic; regulates potassiu... ADP-ribosylation factor-like protein 1 9 141   0
BUD14 YAR014C Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cort...   8 29   0
NPT1 YOR209C Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosyn... nicotinate phosphoribosyltransferase 7 142   0.0004
COG5 YNL051W Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   7 89   0
COG7 YGL005C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   6 20   0
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to ...   6 19   0.0386
ISW1 YBR245C Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodelin... ATPase component of a four subunit chromatin remodeling complex 6 96   0.1708
CDH1 YGL003C Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/... required for Clb2 and Ase1 degradation 6 92   0.0002
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   6 19   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 6 56   0.0005
USA1 YML029W Protein that interacts in the two-hybrid system with the U1 snRNP-specific prote... pre-mRNA splicing factor (putative) 6 39   0
HYS2 YJR006W DNA polymerase III (delta) subunit, essential for cell viability; involved in DN... DNA polymerase delta subunit 6 17   0
HST3 YOR025W Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved alo...   6 74   0.0038
RAD17 YOR368W Checkpoint protein, involved in the activation of the DNA damage and meiotic pac... 3--5-exonuclease (putative) 5 85   0.0012
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric...   5 71   0.0027
ESC2 YDR363W Protein involved in mating-type locus silencing, interacts with Sir2p; probably ...   5 74   0
DDC1 YPL194W DNA damage checkpoint protein, part of a PCNA-like complex required for DNA dama...   5 67   0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   5 32   0
HOC1 YJR075W Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit... mannosyltransferase (putative) 5 64 0.0541 0.0001
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein involved in coordinate... phosphatidylcholine transfer protein|phosphatidylinositol transfer protein 5 139   0.0065
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, ... mannosyltransferase complex component 5 31   0
PIF1 YML061C DNA helicase involved in telomere formation and elongation; acts as a catalytic ... 5--3- DNA helicase 5 104   0.1887
VAC7 YNL054W Integral vacuolar membrane protein involved in vacuole inheritance and morpholog...   5 27   0.1887
ERG3 YLR056W C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into e... C-5 sterol desaturase 5 43   0
CBK1 YNL161W Serine/threonine protein kinase that regulates cell morphogenesis pathways; invo... serine/threonine protein kinase 5 41   0.0009
ORC2 YBR060C Subunit of the origin recognition complex, which directs DNA replication by bind... origin recognition complex subunit 2 5 68   0.019
CDC2 YDL102W Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replicat... DNA polymerase III catalytic (delta) subunit 5 90   0.0504
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   5 48   0

Service provided by the Mike Tyers Laboratory