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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:28
Sym Orf Description Function No All Z_score hyperg
RAD53 YPL153C Protein kinase, required for cell-cycle arrest in response to DNA damage; activa... protein kinase 8 132   NAN
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 8 62   0.1591
SAP30 YMR263W Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is in...   6 32 -35.5536 0.1762
BRE1 YDL074C E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, r...   6 27   0
SIN3 YOL004W DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in tran... DNA binding protein|involved in transcriptional regulation 6 75   0
UME1 YPL139C Negative regulator of meiosis, required for repression of a subset of meiotic ge... transcriptional modulator 6 39   0.005
RXT2 YBR095C Protein possibly involved in cell fusion and invasive growth   6 33   0.0114
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   6 47   0.0097
SDS3 YIL084C Component of the Rpd3p/Sin3p deacetylase complex required for its structural int...   6 33   0.0277
PHO23 YNL097C Probable component of the Rpd3 histone deacetylase complex, involved in transcri...   5 36   0.1199
RXT3 YDL076C Protein of unknown function, may be involved in chromatin silencing   5 27   0.0003
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in r... nuclear NAD-dependent deacetylase 4 76   0.0283
DEP1 YAL013W Transcriptional modulator involved in regulation of structural phospholipid bios...   4 26 -32.1117 0.0009
DIA2 YOR080W Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp...   4 47   0.0014
POL2 YNL262W Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA re... DNA polymerase II 4 42   0
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that act...   4 23   0
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes effi... bovine NABC complex component homolog|non-native actin binding complex polypeptide 3|prefoldin complex subunit 4 20 -0.5983 0
LGE1 YPL055C Protein of unknown function; null mutant forms abnormally large cells   4 57 -21.2482 0
CDC45 YLR103C DNA replication initiation factor; recruited to MCM pre-RC complexes at replicat... chromosomal DNA replication initiation protein 4 35   0.0582
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p, which is a s...   4 18   0
CSM3 YMR048W Protein required for accurate chromosome segregation during meiosis   4 29   0
MCM2 YBL023C Protein involved in DNA replication; component of the Mcm2-7 hexameric complex t...   4 65   0
UME6 YDR207C Key transcriptional regulator of early meiotic genes, binds URS1 upstream regula... C6 zinc finger URS1-binding protein 4 40   0.0054
ASH1 YKL185W Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in t...   4 42   0
  YBL104C     3 30   0
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 3 104   0.0003
MSS116 YDR194C DEAD-box protein required for efficient splicing of mitochondrial Group I and II... RNA helicase DEAD box 3 17   0.0016
DED1 YOR204W ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation ...   3 103   0

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