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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:32
Sym Orf Description Function No All Z_score hyperg
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase; activates Cdc28p to pr... B-type cyclin 4 100   0.0769
POL2 YNL262W Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA re... DNA polymerase II 4 46   0
ORC5 YNL261W Subunit of the origin recognition complex, which directs DNA replication by bind... ATP-binding site (putative)|origin recognition complex fifth largest subunit 4 41   0.0005
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric...   4 71   0.0009
SIC1 YLR079W Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, pre...   4 144   0
DDC1 YPL194W DNA damage checkpoint protein, part of a PCNA-like complex required for DNA dama...   4 67   0
RAD17 YOR368W Checkpoint protein, involved in the activation of the DNA damage and meiotic pac... 3--5-exonuclease (putative) 4 85   0.0004
MET7 YOR241W Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of th... folylpolyglutamate synthetase 4 30   0
NPT1 YOR209C Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosyn... nicotinate phosphoribosyltransferase 4 142   0
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for... 100 kDa protein (predicted molecular weight is 120 kDa) with two leucine zipper motifs, coiled-coil region, and some homology to Nup133p|nuclear pore complex subunit 4 66   0.1944
CDC6 YJL194W Essential ATP-binding protein required for DNA replication, component of the pre... pre-initiation complex component 4 64   0.0001
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to... DNA polymerase II C and C- subunits 4 43   0
ORC2 YBR060C Subunit of the origin recognition complex, which directs DNA replication by bind... origin recognition complex subunit 2 4 68   0.0614
URA7 YBL039C Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer... CTP synthase 4 24   0
DPB4 YDR121W Shared subunit of DNA polymerase epsilon and of ISW2/yCHRAC chromatin accessibil... DNA polymerase II (epsilon) 4th subunit 4 44   0
ARG2 YJL071W Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme t... acetylglutamate synthase 4 22   0
RAD24 YER173W Checkpoint protein, involved in the activation of the DNA damage and meiotic pac... cell cycle exonuclease (putative) 4 118   0.0005
GLN3 YER040W Transcriptional activator of genes regulated by nitrogen catabolite repression (... transcriptional activator of nitrogen-regulated genes 4 44   0.0002
RNR1 YER070W Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catal... ribonucleotide reductase, large (R1) subunit 4 44   0
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that act...   4 142   0
KIP3 YGL216W Kinesin-related motor protein involved in mitotic spindle positioning   4 49   0.1991
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA duri... UV endonuclease 2 97   0.0007
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 2 46   0
CDH1 YGL003C Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/... required for Clb2 and Ase1 degradation 2 92   0
PEP12 YOR036W Target membrane receptor (t-SNARE) for vesicular intermediates traveling between... c-terminal TMD|integral membrane protein 2 33   0.0554
VAM3 YOR106W Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in... syntaxin family 2 25   0
ZRG8 YER033C Cytoplasmic protein of unknown function, transcription is induced under conditio...   2 10   0.0001
VPH1 YOR270C Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph... V0 sector subunit|essential for vacuolar acidification and vacuolar H-ATPase activity|vacuolar ATPase V0 domain subunit a (100 kDa)|vacuolar H-ATPase 2 13   0.135
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catal... ribonucleotide reductase, small (R2) subunit 2 46   0.0854
MYO1 YHR023W Type II myosin heavy chain, required for wild-type cytokinesis and cell separati... class II myosin 2 64   0.2829
VPS33 YLR396C ATP-binding protein that is a subunit of the homotypic vacuole fusion and vacuol...   2 37   0.0102
TPP1 YMR156C DNA 3--phosphatase that functions in repair of endogenous damage of double-stran... DNA 3- phosphatase 2 24   0.0979

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