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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:34
Sym Orf Description Function No All Z_score hyperg
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 2 homolog (putative) 8 11   0
PFD1 YJL179W Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and trans... bovine prefoldin subunit 1 homolog (putative) 8 19   0
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex involved in the fol... bovine NABC complex component homolog|non-native actin binding complex polypeptide 6|prefoldin complex subunit 8 20   0
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 5 homolog (putative) 8 14   0
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes effi... bovine NABC complex component homolog|non-native actin binding complex polypeptide 3|prefoldin complex subunit 4 20 -40.6679 0
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 4 homolog (putative) 4 18 -18.3650 0
TUB4 YLR212C Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and... gamma tubulin 4 20   0
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specifici...   3 12   0.0002
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 3 36   0.0844
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 2 145   0
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoin... meiosis-specific serine/threonine protein kinase 2 65   0.0001
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleo...   2 121   0
CLN3 YAL040C G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote... G1 cyclin 2 11 -12.7623 0.1727
PKH2 YOL100W Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   2 51   0
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p; part of ...   2 76   0
PUF6 YDR496C Pumilio-homology domain protein that binds ASH1 mRNA at PUF consensus sequences ...   2 109   0
RCK1 YGL158W Protein kinase involved in the response to oxidative stress; identified as suppr...   2 143   0
PKH3 YDR466W Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 ...   2 43   0
NSP1 YJL041W Essential component of the nuclear pore complex, which mediates nuclear import a... nuclear pore complex subunit 2 68   0
HOS1 YPR068C Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, R...   2 6   0.0002
CDC48 YDL126C ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a ...   2 104   0
PCL9 YDL179W Cyclin, forms a functional kinase complex with Pho85p cyclin-dependent kinase (C...   2 10   0
MSN5 YDR335W Karyopherin involved in nuclear import and export; shown to be responsible for n...   2 57   0.1528
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 2 24   0
  YGL059W     2 94   0
ESA1 YOR244W Histone acetyltransferase catalytic subunit of the native multisubunit complex (... NuA4 complex component|acetyltransferase in the SAS gene family 2 137   0
  YHR113W     2 21   0
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to p... G1 cyclin 2 47   0.1427
SNF4 YGL115W Protein kinase activator found in a complex containing Snf1p and members of the ... associates with Snf1p 2 51   0
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 2 74   0.0019
NUM1 YDR150W Protein required for nuclear migration, localizes to the mother cell cortex and ...   1 20 -0.3807 0
MSC2 YDR205W Member of the cation diffusion facilitator family, localizes to the endoplasmic ...   1 3   0.2775
RPA14 YDR156W RNA polymerase I subunit A14 RNA polymerase I subunit 1 18   0.0003
ATC1 YDR184C Nuclear protein, possibly involved in regulation of cation stress responses and/...   1 10   0.331

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