Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
BRE1 YDL074C E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, r...   6 27   0
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes effi... bovine NABC complex component homolog|non-native actin binding complex polypeptide 3|prefoldin complex subunit 4 20 0.5104 0
LGE1 YPL055C Protein of unknown function; null mutant forms abnormally large cells   4 57 -6.6556 0
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocat... translation elongation factor 2 (EF-2) 2 55   0
SPC110 YDR356W Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; invol... interacts with Spc42p, calmodulin, and a 35 kDa protein|spindle pole body component 2 66   0
NPL3 YDR432W RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytopla... contains RNA recognition motif|nuclear shuttling protein 2 118   0.1344
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   2 49   0.0214
SNT1 YCR033W Subunit of the Set3C deacetylase complex; putative DNA-binding protein   2 20   0
MSH3 YCR092C Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertio... forms a complex with Msh2p to repair insertion-deletion mispairs; redundant with Pms3/Msh6p in repair of insertion-deletion mispairs|mutS homolog 2 11   0.08
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis, forms a complex wit... human GTBP protein homolog 2 30   0
FIR1 YER032W Protein involved in 3- mRNA processing, interacts with Ref2p; potential Cdc28p s... participant in 3- mRNA processing (putative) 2 26   0.0959
BEM2 YER155C Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton o... rho GTPase activating protein (GAP) 2 47   0
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 2 104   0.0001
MGM101 YJR144W Protein involved in mitochondrial genome maintenance; component of the mitochond... mitochondrial nucleoid protein 2 21   0.0296
SPC42 YKL042W Central plaque component of spindle pole body (SPB); involved in SPB duplication... spindle pole body component 2 39   0
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   2 109   0
RFA3 YJL173C Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... replication factor-A subunit 3 2 37   0
RXT2 YBR095C Protein possibly involved in cell fusion and invasive growth   2 33   0.2866
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts... gamma-tubulin complex component 2 15   0
KOG1 YHR186C Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that ...   2 35   0
TAO3 YIL129C Protein involved in cell morphogenesis and proliferation, associated with protei...   2 11   0.0138
AKL1 YBR059C Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; ...   2 97   0.0002
ISW1 YBR245C Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodelin... ATPase component of a four subunit chromatin remodeling complex 2 66   0.0626
UME1 YPL139C Negative regulator of meiosis, required for repression of a subset of meiotic ge... transcriptional modulator 2 39   0.2803
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   2 47   0.0001
SIN3 YOL004W DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in tran... DNA binding protein|involved in transcriptional regulation 2 75   0
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 2 62   0.0073
UME6 YDR207C Key transcriptional regulator of early meiotic genes, binds URS1 upstream regula... C6 zinc finger URS1-binding protein 2 40   0.1365
SDS3 YIL084C Component of the Rpd3p/Sin3p deacetylase complex required for its structural int...   2 33   0.2666
ASH1 YKL185W Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in t...   2 42   0
SAP30 YMR263W Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is in...   2 32 -1.7313 0.0537
KIN3 YAR018C Nonessential protein kinase with unknown cellular role protein kinase 2 25   0
BOI1 YBL085W Protein implicated in polar growth, functionally redundant with Boi2p; interacts...   2 67   0
SPT5 YML010W Protein that forms a complex with Spt4p and mediates both activation and inhibit... transcription factor 2 145   0.2753
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p, which is a s...   2 18   0

Service provided by the Mike Tyers Laboratory