Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:31
Sym Orf Description Function No All Z_score hyperg
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 2 homolog (putative) 8 11   0
PFD1 YJL179W Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and trans... bovine prefoldin subunit 1 homolog (putative) 8 19   0
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex involved in the fol... bovine NABC complex component homolog|non-native actin binding complex polypeptide 6|prefoldin complex subunit 8 20   0
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 5 homolog (putative) 8 14   0
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 4 homolog (putative) 4 18 -7.6278 0
TUB4 YLR212C Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and... gamma tubulin 4 20   0
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes effi... bovine NABC complex component homolog|non-native actin binding complex polypeptide 3|prefoldin complex subunit 4 20 -6.5470 0
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   2 98   0
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p, which is a s...   2 18   0
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that amin... tyrosine-tRNA ligase 2 21   0
CDC48 YDL126C ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a ...   2 104   0
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 2 74   0.0019
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoin... meiosis-specific serine/threonine protein kinase 2 65   0.0001
PKH2 YOL100W Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   2 51   0
  YPL150W     2 52   0.0929
NSP1 YJL041W Essential component of the nuclear pore complex, which mediates nuclear import a... nuclear pore complex subunit 2 68   0
PKH3 YDR466W Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 ...   2 43   0
RCK1 YGL158W Protein kinase involved in the response to oxidative stress; identified as suppr...   2 143   0
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 2 145   0
BRE1 YDL074C E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, r...   2 27   0
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p; part of ...   2 76   0
ESA1 YOR244W Histone acetyltransferase catalytic subunit of the native multisubunit complex (... NuA4 complex component|acetyltransferase in the SAS gene family 2 137   0
HOS1 YPR068C Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, R...   2 6   0.0002
RAD53 YPL153C Protein kinase, required for cell-cycle arrest in response to DNA damage; activa... protein kinase 2 132   0
  YGL059W     2 94   0
PCL9 YDL179W Cyclin, forms a functional kinase complex with Pho85p cyclin-dependent kinase (C...   2 10   0
  YHR113W     2 21   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 2 24   0
SNF4 YGL115W Protein kinase activator found in a complex containing Snf1p and members of the ... associates with Snf1p 2 51   0
MSN5 YDR335W Karyopherin involved in nuclear import and export; shown to be responsible for n...   2 57   0.1528
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   1 42   0

Service provided by the Mike Tyers Laboratory