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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
POL2 YNL262W Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA re... DNA polymerase II 4 42   0
CSM3 YMR048W Protein required for accurate chromosome segregation during meiosis   4 29   0
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that act...   4 23   0
RAD53 YPL153C Protein kinase, required for cell-cycle arrest in response to DNA damage; activa... protein kinase 4 132   0
DIA2 YOR080W Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp...   4 47   0.0014
MCM2 YBL023C Protein involved in DNA replication; component of the Mcm2-7 hexameric complex t...   4 65   0
CDC45 YLR103C DNA replication initiation factor; recruited to MCM pre-RC complexes at replicat... chromosomal DNA replication initiation protein 4 35   0.0582
SPC19 YDR201W Essential subunit of the DASH microtubule ring complex, couples kinetochores to ... spindle pole component 2 38   0.0014
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required f... DNA polymerase epsilon subunit B 2 53   0
CDC54 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-...   2 57   0.0001
CMK2 YOL016C Calmodulin-dependent protein kinase; may play a role in stress response, many CA... calmodulin-dependent protein kinase 2 70   0
HDA2 YDR295C Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deace...   2 21   0
BST1 YFL025C GPI inositol deacylase of the ER that negatively regulates COPII vesicle formati...   2 3   0
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p, which is a s...   2 18   0
SMC3 YJL074C Subunit of the multiprotein cohesin complex required for sister chromatid cohesi... SMC chromosomal ATPase family member 2 67   0
TUB3 YML124C Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which... alpha-tubulin 2 49   0
RPN3 YER021W Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to t... 26S proteasome regulatory module component 2 86   0.0014
GWT1 YJL091C Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol ...   2 8   0
MCM3 YEL032W Protein involved in DNA replication; component of the Mcm2-7 hexameric complex t...   2 37   0
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member; signal tra...   2 40   0
KAR2 YJL034W ATPase involved in protein import into the ER, also acts as a chaperone to media... HSP70 family|mammalian BiP (GRP78 or HSPA5) homolog 2 58   0.0002
CTF4 YPR135W Chromatin-associated protein, required for sister chromatid cohesion; interacts ... DNA polymerase alpha binding protein 2 38   0
PRP9 YDL030W Subunit of the SF3a splicing factor complex, required for spliceosome assembly; ... RNA splicing factor 2 77   0
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to ... subunit of the GINS complex 2 17   0
BNI1 YNL271C Formin, nucleates the formation of linear actin filaments, involved in cell proc... formin, involved in spindle orientation 2 44   0
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to ... subunit of the GINS complex 2 35   0.0008
PAC11 YDR488C Dynein intermediate chain, acts in the cytoplasmic dynein pathway, forms cortica...   2 9   0.2855
DNM1 YLL001W Dynamin-related GTPase required for mitochondrial fission and the maintenance of... similar to dynamin GTPase 2 20   0.2663
RIO2 YNL207W Essential serine kinase involved in the processing of the 20S pre-rRNA into matu...   2 70   0
NUF2 YOL069W Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (...   2 56   0.0014
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   2 98   0
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that amin... tyrosine-tRNA ligase 2 21   0
NNF1 YJR112W Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p...   2 50   0
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppresso...   2 70   0
KAR9 YPL269W Karyogamy protein required for correct positioning of the mitotic spindle and fo...   2 30   0
SCS2 YER120W Integral ER membrane protein that regulates phospholipid metabolism via an inter...   2 25   0
SIR3 YLR442C Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tai... silencing regulator at HML, HMR, and telomeres 1 56   0.042
ASC1 YMR116C WD repeat protein (G-beta like protein) involved in translation regulation; requ... G-beta like protein 1 73   0.3762

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