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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 5 homolog (putative) 8 14   0
PFD1 YJL179W Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and trans... bovine prefoldin subunit 1 homolog (putative) 8 19   0
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 2 homolog (putative) 8 11   0
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex involved in the fol... bovine NABC complex component homolog|non-native actin binding complex polypeptide 6|prefoldin complex subunit 8 20   0
BRE1 YDL074C E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, r...   6 27   0
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 4 homolog (putative) 4 18 -16.4164 0
CSM3 YMR048W Protein required for accurate chromosome segregation during meiosis   4 29   0
POL2 YNL262W Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA re... DNA polymerase II 4 42   0
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that act...   4 23   0
TUB4 YLR212C Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and... gamma tubulin 4 20   0
DIA2 YOR080W Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp...   4 47   0.0014
CDC45 YLR103C DNA replication initiation factor; recruited to MCM pre-RC complexes at replicat... chromosomal DNA replication initiation protein 4 35   0.0582
RAD53 YPL153C Protein kinase, required for cell-cycle arrest in response to DNA damage; activa... protein kinase 4 132   0
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes effi... bovine NABC complex component homolog|non-native actin binding complex polypeptide 3|prefoldin complex subunit 4 20 -22.3294 0
MCM2 YBL023C Protein involved in DNA replication; component of the Mcm2-7 hexameric complex t...   4 65   0
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 4 62   0.0504
LGE1 YPL055C Protein of unknown function; null mutant forms abnormally large cells   4 57 -17.8320 0
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in r... nuclear NAD-dependent deacetylase 3 76   0.0114
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 3 104   0.0003
RFA3 YJL173C Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... replication factor-A subunit 3 2 37   0
NET1 YJL076W Core subunit of the RENT complex, which is a complex involved in nucleolar silen...   2 68   0.0002
MGM101 YJR144W Protein involved in mitochondrial genome maintenance; component of the mitochond... mitochondrial nucleoid protein 2 21   0.0296
KOG1 YHR186C Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that ...   2 35   0
TAO3 YIL129C Protein involved in cell morphogenesis and proliferation, associated with protei...   2 11   0.0138
MSH2 YOL090W Protein that forms heterodimers, with Msh3p and Msh6p, that bind to DNA mismatch... mutS homolog 2 37   0.0174
BEM2 YER155C Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton o... rho GTPase activating protein (GAP) 2 47   0
SPC42 YKL042W Central plaque component of spindle pole body (SPB); involved in SPB duplication... spindle pole body component 2 39   0
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts... gamma-tubulin complex component 2 15   0
CNM67 YNL225C Component of the spindle pole body outer plaque; required for spindle orientatio...   2 29   0.0026
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   2 109   0
BUB2 YMR055C Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that...   2 15   0.0001
FIR1 YER032W Protein involved in 3- mRNA processing, interacts with Ref2p; potential Cdc28p s... participant in 3- mRNA processing (putative) 2 26   0.0959
RAD52 YML032C Protein that stimulates strand exchange by facilitating Rad51p binding to single...   2 33   0
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of g...   2 7   0.0016
TOP2 YNL088W Essential type II topoisomerase, relieves torsional strain in DNA by cleaving an... topoisomerase II 2 49   0.166

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