Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:30
Sym Orf Description Function No All Z_score hyperg
SIC1 YLR079W Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, pre...   8 45   0.0003
RGA1 YOR127W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... rho GTPase activating protein (GAP) 8 24   0
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton o... rho GTPase activating protein (GAP) 8 21   0
SKP1 YDR328C Evolutionarily conserved kinetochore protein that is part of multiple protein co...   8 137   0
FAR1 YJL157C Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to... Cdc28p kinase inhibitor 8 37   0
CKS1 YBR135W Subunit of the Cdc28 protein kinase, required for mitotic proteolysis, may also ... Cdc28 protein kinase subunit 8 56   0
CDC48 YDL126C ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a ...   8 104   0
GRR1 YJR090C F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p ...   8 42   0.0955
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase; activates Cdc28p to pr... B-type cyclin 4 10   0
CDC4 YFL009W F-box protein required for G1/S and G2/M transition, associates with Skp1p and C... ubiquitin ligase subunit 4 30   0
CDH1 YGL003C Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/... required for Clb2 and Ase1 degradation 4 36   0
CDC53 YDL132W Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, a...   4 59   0.0013
BMH2 YDR099W 14-3-3 protein, minor isoform; binds proteins and DNA, involved in regulation of... member of conserved eukaryotic 14-3-3 gene family 4 119   0
DIG2 YDR480W Regulatory protein of unknown function, pheromone-inducible, involved in the reg... MAP kinase-associated protein 4 36   0
ECM10 YEL030W Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, pl...   4 27   0
SRL3 YKR091W Cytoplasmic protein that, when overexpressed, suppresses the lethality of a rad5...   4 4   0
ATP3 YBR039W Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a la... ATP synthase gamma subunit 4 33   0
CDC34 YDR054C Ubiquitin-conjugating enzyme or E2; together with Skp1p, Rbx1p, Cdc53p, and an F... ubiquitin-conjugating enzyme 4 42   0.0415
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar bud... GTPase activating protein (GAP) for Rsr1p/Bud1p 4 6   0
ACE2 YLR131C Transcription factor that activates expression of early G1-specific genes, local... zinc finger transcription factor 4 24   0
ZDS1 YMR273C Protein that interacts with silencing proteins at the telomere, involved in tran...   4 39   0.1691
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); i... adenylate cyclase regulatory protein 4 65   0.0653
BUD3 YCL014W Protein involved in bud-site selection and required for axial budding pattern; l...   4 42   0
ACM1 YPL267W Protein of unknown function, potential Cdc28p substrate   4 13   0
VAC14 YLR386W Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of traffi... Activator of Fab1p 4 33   0.0065
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   4 10   0.006
MLF3 YNL074C Serine-rich protein of unknown function; overproduction suppresses the growth in...   4 16   0
SIN3 YOL004W DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in tran... DNA binding protein|involved in transcriptional regulation 4 75   0
  YPL014W     4 3   0
STE20 YHL007C Signal transducing kinase of the PAK (p21-activated kinase) family, involved in ...   3 117   0.0215

Service provided by the Mike Tyers Laboratory