Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 20   0
FUS3 YBL016W Mitogen-activated protein kinase involved in mating pheromone response; activate... CDC28/cdc2 related protein kinase 6 32   0
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   6 4   0
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 6 26   0
SOY1 YBR194W Protein proposed to be associated with the nuclear pore complex   3 14   0.028
SWE1 YJL187C Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase... tyrosine kinase 3 59   0.0734
VPS24 YKL041W One of four subunits of the endosomal sorting complex required for transport III...   3 43   0.0421
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, ... mannosyltransferase complex component 3 31   0
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, activat... basic leucine zipper (bZIP) transcription factor 3 6   0
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 3 49 -0.7068 0.0898
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 3 59   0.0002
MST1 YKL194C Mitochondrial threonyl-tRNA synthetase   3 4   0.0001
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 3 28   0
SKI2 YLR398C Putative RNA helicase, involved in exosome mediated 3- to 5- mRNA degradation an... antiviral protein|helicase (putative) 3 28   0.2376
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor required for oxidative stress t... jun-like transcription factor 3 39   0.2258
STE11 YLR362W Signal transducing MEK kinase involved in pheromone response and pseudohyphal/in...   3 70   0.0041
TEC1 YBR083W Transcription factor required for full Ty1 epxression, Ty1-mediated gene activat... TEA/ATTS DNA-binding domain family transcription factor 3 17   0.225
SIC1 YLR079W Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, pre...   3 144   0
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   3 10   0
STE20 YHL007C Signal transducing kinase of the PAK (p21-activated kinase) family, involved in ...   3 60   0.0215
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response; functions as part ... Ser/Thr Kinase 3 67   0.0001
STE7 YDL159W Signal transducing MAP kinase kinase involved in pheromone response, where it ph... MAP kinase kinase (MEK) 3 17   0
CDC37 YDR168W Essential Hsp90p co-chaperone; necessary for passage through the START phase of ...   3 60   0
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthes... glycerol-3-phosphate dehydrogenase 3 13   0
TUP1 YCR084C General repressor of transcription, forms complex with Cyc8p, involved in the es...   3 16   0
STE50 YCL032W Protein involved in mating response, invasive/filamentous growth, and osmotolera... contains SAM (sterile alpha motif) 3 26   0
LRE1 YCL051W Protein involved in control of cell wall structure and stress response; inhibits...   3 10   0
SEM1 YDR363W-A Component of the lid subcomplex of the regulatory subunit of the 26S proteasome;...   3 43   0
ERD1 YDR414C Predicted membrane protein required for the retention of lumenal endoplasmic ret...   3 83   0.0576
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppre... type 2C protein phosphatase 3 4   0.012
CYC8 YBR112C General transcriptional co-repressor, acts together with Tup1p; also acts as par...   3 24   0.0987
EMP24 YGL200C Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicl... type I transmembrane protein 3 25   0
SHO1 YER118C Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP... transmembrane osmosensor 3 17   0
SNF1 YDR477W AMP-activated serine/threonine protein kinase found in a complex containing Snf4... serine/threonine kinase 3 79   0
ITR1 YDR497C Myo-inositol transporter with strong similarity to the minor myo-inositol transp... myo-inositol transporter 3 24   0
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity and respon...   3 7   0
VPS9 YML097C A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar prote...   3 88   0.0009
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 3 13   0
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 3 38   0
SSK1 YLR006C Cytoplasmic response regulator, part of a two-component signal transducer that m... two-component signal transducer that with Sln1p regulates osmosensing MAP kinase cascade(suppressor of sensor kinase) 3 23   0

Service provided by the Mike Tyers Laboratory