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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 10 24   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 10 25   NAN
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 10 36   0.0391
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26   0.14
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   10 15   0.0832
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   7 51   0
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerat... 6-phosphogluconate dehydrogenase 5 29   0
OYE2 YHR179W Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), ho... NAPDH dehydrogenase (old yellow enzyme), isoform 2 5 25   0
KIC1 YHR102W Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possi...   5 22   0
EGD2 YHR193C Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) in... GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog 5 33   0
LYS12 YIL094C Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for t... homo-isocitrate dehydrogenase 5 51   0
PRE3 YJL001W 20S proteasome beta-type subunit, responsible for cleavage after acidic residues... 20S proteasome subunit 5 39   0
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 5 41   0
GAL7 YBR018C Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UD... galactose-1-phosphate uridyl transferase 5 9   0
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide ... Hsp70 family 5 16   0.1056
MPM1 YJL066C Mitochondrial membrane protein of unknown function, contains no hydrophobic stre...   5 11   0
RPA34 YJL148W RNA polymerase I subunit A34.5   5 41   0
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 5 74   0
RPT3 YDR394W One of six ATPases of the 19S regulatory particle of the 26S proteasome involved...   5 99   0
ROM1 YGR070W GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal wit...   5 5   0
USE1 YGL098W Essential SNARE protein localized to the ER, involved in retrograde traffic from...   5 19   0
  YFR038W     5 7   0.0188
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 10   0
AHA1 YDR214W Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to ... Hsp90 system cochaperone; Aha1 binds to the middle domain of Hsp90 and improves client protein activation in vivo 5 51   0
EBS1 YDR206W Protein of unknown function, contains a putative RNA recognition motif, deletion...   5 16   0
PIL1 YGR086C Integral membrane protein that along with Lsp1p is a primary component of eisoso...   5 80   0
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 20   0
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pa... GTP-cyclohydrolase I 5 25   0
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid required for ... proteasome regulatory particle subunit 5 66   0.0222
PDC6 YGR087C Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, d... pyruvate decarboxylase isozyme 5 9   0
PRS4 YBL068W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 6   0
SKG3 YLR187W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   5 16   0
RTF1 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly... nuclear protein 5 36   0.0954
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 5 38   0.006
DIG1 YPL049C Regulatory protein of unknown function, constitutively-expressed, involved in th... MAP kinase-associated protein 5 54   0

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