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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
CDC28 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternat... cyclin-dependent protein kinase 10 110   0.0665
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 10 27   0
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 10 46   0
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   10 31   0.1159
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 8 16   0
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   8 65   0.0842
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 7 126   0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   7 64   0.0252
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 7 28   0.0001
GPI16 YHR188C Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase c... GPI transamidase component, human PIG-T homologue 5 3   0
GGA2 YHR108W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 5 20   0
ERG7 YHR072W Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squal... 2,3-oxidosqualene-lanosterol cyclase 5 5   0
RPC10 YHR143W-A RNA polymerase subunit, found in RNA polymerase complexes I, II, and III RNA polymerase II subunit 5 15   0
NCP1 YHR042W NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated ... NADP-cytochrome P450 reductase 5 11   0
CNA1 YLR433C Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calci... calcineurin subunit A 5 12   0.079
DIE2 YGR227W Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in th... glucosyltransferase 5 48   0.0043
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 5 16   0
BNR1 YIL159W Formin, nucleates the formation of linear actin filaments, involved in cell proc...   5 40   0.0128
  ETG5598     5 1   0
MCD4 YKL165C Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multime...   5 6   0
STM1 YLR150W Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts wit... purine motif triplex-binding protein 5 23   0.0017
SIS2 YKR072C Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion ...   5 50   0.1812
ERG27 YLR100W 3-keto sterol reductase, catalyzes the last of three steps required to remove tw... 3-keto sterol reductase 5 2   0
  YKL161C     5 5   0.0912
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of gluc... glucoseamine-6-phosphate synthase|glutamine_fructose-6-phosphate amidotransferase 5 6   0
PRP16 YKR086W RNA helicase in the DEAH-box family involved in the second catalytic step of spl... ATP-binding protein (putative) 5 13   0
YUR1 YJL139C Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; loc... mannosyltransferase 5 29   0.1313
INO1 YJL153C Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and ... L-myo-inositol-1-phosphate synthase 5 7   0
  YKL037W     5 12   0.1349
GPI1 YGR216C Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidyli...   5 4   0
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase, has similarity to an alternate ca... 1,3-beta-D-glucan synthase 5 9   0.0074
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   5 62   0
ROT2 YBR229C Glucosidase II catalytic subunit required for normal cell wall synthesis; mutati... glucosidase II 5 92   0.0018
ALG7 YBR243C UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to... UDP-N-acetyl-glucosamine-1-P transferase (GPT) 5 10   0
SYP1 YCR030C Protein with a potential role in actin cytoskeletal organization; overexpression...   5 9   0
SWI5 YDR146C Transcription factor that activates transcription of genes expressed in G1 phase... transcriptional activator 5 43   0.0114

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