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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:34
Sym Orf Description Function No All Z_score hyperg
SIC1 YLR079W Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, pre...   14 45   0.0246
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   13 51   0
STE20 YHL007C Signal transducing kinase of the PAK (p21-activated kinase) family, involved in ...   13 117   0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 11 13   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 10 36   0.0391
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26   0.14
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 10 25   NAN
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   10 15   0.0832
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 10 24   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   10 34   0
DIG1 YPL049C Regulatory protein of unknown function, constitutively-expressed, involved in th... MAP kinase-associated protein 9 54   0
CKS1 YBR135W Subunit of the Cdc28 protein kinase, required for mitotic proteolysis, may also ... Cdc28 protein kinase subunit 8 56   0
GRR1 YJR090C F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p ...   8 42   0.0955
FAR1 YJL157C Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to... Cdc28p kinase inhibitor 8 37   0
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton o... rho GTPase activating protein (GAP) 8 21   0
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spin... ubiquitin-like protein 8 37   0
RGA1 YOR127W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... rho GTPase activating protein (GAP) 8 24   0
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 8 45   0
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 8 8   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
CDC48 YDL126C ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a ...   6 104   0
HOT1 YMR172W Transcription factor required for the transient induction of glycerol biosynthet... nuclear protein 6 16   0
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 6 38   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 16   0
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   6 48   0
  YFR038W     5 7   0.0188
PIL1 YGR086C Integral membrane protein that along with Lsp1p is a primary component of eisoso...   5 80   0
USE1 YGL098W Essential SNARE protein localized to the ER, involved in retrograde traffic from...   5 19   0
ROM1 YGR070W GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal wit...   5 5   0

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