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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
CDC28 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternat... cyclin-dependent protein kinase 18 110   0
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   13 102   0.1158
BCK2 YER167W Protein rich in serine and threonine residues involved in protein kinase C signa...   13 47   0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   13 64   0.1284
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 13 28   0.0105
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to p... G1 cyclin 13 84   0
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 10 46   0
FUS3 YBL016W Mitogen-activated protein kinase involved in mating pheromone response; activate... CDC28/cdc2 related protein kinase 10 32   0
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   10 31   0.1159
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 10 27   0
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 10 126   0
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn... galactosyltransferase 9 63   NAN
CYK3 YDL117W SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring...   9 34   0.0017
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 9 41   NAN
WHI3 YNL197C RNA binding protein that binds to and sequesters the G1 cyclin CLN3 mRNA; regula... RNA binding protein (putative) 9 22   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 9 140   0
CDC12 YHR107C Component of the septin ring of the mother-bud neck that is required for cytokin... 10 nm filament component of mother-bud neck|septin 9 79   0.0118
ZDS1 YMR273C Protein that interacts with silencing proteins at the telomere, involved in tran...   9 39   0.0491
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 9 93   0
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 8 115   0.0137
MSN5 YDR335W Karyopherin involved in nuclear import and export; shown to be responsible for n...   8 48   0.0252
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 8 16   0
RRD1 YIL153W Activator of the phosphotyrosyl phosphatase activity of PP2A; regulates G1 phase...   8 24   0
MCM1 YMR043W Transcription factor involved in cell-type-specific transcription and pheromone ... contains the 56 amino-acid MADS (MCM1, AG, DEFAm SRF)-box motif within its DNA binding domain, plays a central role in the formation of both repressor and activator complexes|transcription factor 8 14   0
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 8 81   0
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppre... type 2C protein phosphatase 8 4   0.1437
CDH1 YGL003C Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/... required for Clb2 and Ase1 degradation 8 92   0.0017
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   8 65   0.0842
ERD1 YDR414C Predicted membrane protein required for the retention of lumenal endoplasmic ret...   8 83   0
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring, proposed ... serine/threonine kinase (putative) 8 29   0
CLN3 YAL040C G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote... G1 cyclin 8 71   0
STE4 YOR212W G protein beta subunit, forms a dimer with Ste18p to activate the mating signali... G protein beta subunit|coupled to mating factor receptor 7 42   0
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   7 140   0
BEM2 YER155C Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton o... rho GTPase activating protein (GAP) 7 74   0
STE11 YLR362W Signal transducing MEK kinase involved in pheromone response and pseudohyphal/in...   7 70   0

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