Compound Information | SONAR Target prediction | Name: | AMINOBENZTROPINE | Unique Identifier: | SPE02300334 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 296.238 g/mol | X log p: | 18.29 (online calculus) | Lipinksi Failures | 1 | TPSA | 12.47 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 3 | Rotatable Bond Count: | 4 | Canonical Smiles: | CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccccc1N | Source: | synthetic | Reference: | J Biol Chem 258: 13575 (1983) | Therapeutics: | muscarinic agonist |
Species: |
4932 |
Condition: |
BY4743 |
Replicates: |
2 |
Raw OD Value: r im |
0.9610±0 |
Normalized OD Score: sc h |
0.9930±0 |
Z-Score: |
0.6206±0 |
p-Value: |
0.534864 |
Z-Factor: |
-7.46793 |
Fitness Defect: |
0.6257 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | Spectrum_ED | Plate Number and Position: | 25|C9 | Drug Concentration: | 50.00 nM | OD Absorbance: | 595 nm | Robot Temperature: | 30.00 Celcius | Date: | 2012-05-28 YYYY-MM-DD | Plate CH Control (+): | 0.0985±0.00753 | Plate DMSO Control (-): | 0.9495±0.01455 | Plate Z-Factor: | 0.9222 |
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DBLink | Rows returned: 2 | |
2143 |
2-[(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)oxy-phenyl-methyl]aniline |
6603695 |
2-[(S)-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]oxy-phenyl-methyl]aniline |
internal high similarity DBLink | Rows returned: 1 | |
active | Cluster 2609 | Additional Members: 7 | Rows returned: 2 | |
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