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Compound InformationSONAR Target prediction
Name:

IRINOTECAN HYDROCHLORIDE

Unique Identifier:SPE01505821
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C33ClH39N4O6
Molecular Weight:583.829 g/mol
X log p:  (online calculus)
Lipinksi Failures
TPSA
Hydrogen Bond Donor Count:
Hydrogen Bond Acceptors Count:
Rotatable Bond Count:
Canonical Smiles:Cl.CCc1c2CN3C(=O)C4COC(=O)C(O)(CC)C=4C=C3c2nc2ccc(OC(=O)N3CCC(CC3)N3CC
CCC3)cc21
Source:semisynthetic; U-101440
Therapeutics:antineoplastic; topoisomerase I inhibitor

Found: 91 nonactive as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> [91]
Species: 4932
Condition: AAT2
Replicates: 2
Raw OD Value: r im 0.7521±0.0000707107
Normalized OD Score: sc h 1.0224±0.00431023
Z-Score: 1.1890±0.203023
p-Value: 0.239246
Z-Factor: -2.29642
Fitness Defect: 1.4303
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:5|D10
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.70 Celcius
Date:2008-04-08 YYYY-MM-DD
Plate CH Control (+):0.0402±0.00073
Plate DMSO Control (-):0.7159±0.01647
Plate Z-Factor:0.9139
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 1530 | Additional Members: 9 | Rows returned: 6
SPE01504123 0.178082191780822
LAT002A02 0
LOPAC 00814 0
SPE01502232 0
Prest102 0
LAT003C09 0

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