Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

ROLITETRACYCLINE

Unique Identifier:SPE01505684
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C27H33N3O8
Molecular Weight:494.304 g/mol
X log p:  (online calculus)
Lipinksi Failures
TPSA
Hydrogen Bond Donor Count:
Hydrogen Bond Acceptors Count:
Rotatable Bond Count:
Canonical Smiles:CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(=C1O)C(=O)NCN1CCCC1)C(=O)c1c(O)cccc1C3(
C)O
Source:semisynthetic; SQ-15659
Therapeutics:antibacterial

Found: 7 active | as graph: single | with analogs << Back 1 2 3 4 5 6 7
Species: 4932
Condition: VAM3
Replicates: 2
Raw OD Value: r im 0.5687±0.00770746
Normalized OD Score: sc h 0.8488±0.00654466
Z-Score: -4.5960±0.013798
p-Value: 0.00000431026
Z-Factor: 0.504233
Fitness Defect: 12.3545
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:21|D7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.10 Celcius
Date:2008-04-09 YYYY-MM-DD
Plate CH Control (+):0.040275000000000005±0.00045
Plate DMSO Control (-):0.6473249999999999±0.01202
Plate Z-Factor:0.9359
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 12393 | Additional Members: 20 | Rows returned: 161 2 3 Next >> 
LOPAC 00607 0.554347826086957
LAT004C03 0.554347826086957
SPE01500414 0.448275862068966
Prest626 0.448275862068966
Prest235 0.353658536585366
LAT001B08 0.353658536585366

Service provided by the Mike Tyers Laboratory