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Compound InformationSONAR Target prediction
Name:

ROLITETRACYCLINE

Unique Identifier:SPE01505684
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C27H33N3O8
Molecular Weight:494.304 g/mol
X log p:  (online calculus)
Lipinksi Failures
TPSA
Hydrogen Bond Donor Count:
Hydrogen Bond Acceptors Count:
Rotatable Bond Count:
Canonical Smiles:CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(=C1O)C(=O)NCN1CCCC1)C(=O)c1c(O)cccc1C3(
C)O
Source:semisynthetic; SQ-15659
Therapeutics:antibacterial

Found: 7 active | as graph: single | with analogs << Back 1 2 3 4 5 6 7 Next >> 
Species: 4932
Condition: GIM4
Replicates: 2
Raw OD Value: r im 0.5482±0.00601041
Normalized OD Score: sc h 0.7317±0.00861991
Z-Score: -12.4594±0.246341
p-Value: 5.50366e-35
Z-Factor: 0.643578
Fitness Defect: 78.8851
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:21|D7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.80 Celcius
Date:2008-03-20 YYYY-MM-DD
Plate CH Control (+):0.04015±0.00085
Plate DMSO Control (-):0.7235±0.01679
Plate Z-Factor:0.9195
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

active | Cluster 12393 | Additional Members: 20 | Rows returned: 3
Prest1244 0.490196078431373
Prest1045 0.452631578947368
Prest60 0

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