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Compound InformationSONAR Target prediction
Name:

ROLITETRACYCLINE

Unique Identifier:SPE01505684
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C27H33N3O8
Molecular Weight:494.304 g/mol
X log p:  (online calculus)
Lipinksi Failures
TPSA
Hydrogen Bond Donor Count:
Hydrogen Bond Acceptors Count:
Rotatable Bond Count:
Canonical Smiles:CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(=C1O)C(=O)NCN1CCCC1)C(=O)c1c(O)cccc1C3(
C)O
Source:semisynthetic; SQ-15659
Therapeutics:antibacterial

Found: 7 active | as graph: single | with analogs 1 2 3 4 5 6 7 Next >> 
Species: 4932
Condition: FET3
Replicates: 2
Raw OD Value: r im 0.6263±0.0197283
Normalized OD Score: sc h 0.8793±0.0226059
Z-Score: -5.0536±0.74108
p-Value: 0.00000296708
Z-Factor: -0.0122285
Fitness Defect: 12.7279
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:21|D7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.10 Celcius
Date:2008-01-10 YYYY-MM-DD
Plate CH Control (+):0.04195±0.00022
Plate DMSO Control (-):0.67405±0.01265
Plate Z-Factor:0.9421
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 12393 | Additional Members: 20 | Rows returned: 16<< Back 1 2 3 Next >> 
SPE01500226 0.353658536585366
LAT003H09 0.353658536585366
LOPAC 00845 0.353658536585366
LAT002E04 0.294871794871795
Prest434 0.294871794871795
SPE01500566 0.294871794871795

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