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Compound InformationSONAR Target prediction
Name:

CURCUMIN

Unique Identifier:SPE01505345
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C21H20O6
Molecular Weight:348.221 g/mol
X log p:  (online calculus)
Lipinksi Failures
TPSA
Hydrogen Bond Donor Count:
Hydrogen Bond Acceptors Count:
Rotatable Bond Count:
Canonical Smiles:COc1cc(C=CC(O)=CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O
Class:aromatic
Source:Curcuma spp
Reference:Ber 51: 1347 (1918); J Pharm Pharmacol 5: 448 (1953); Cancer Res 51:813 (1991)
Therapeutics:antiedemic, antiinflammatory, bile stimulant; antibacterial, antifungal,
lipo/cyclooxygenase inhibitor

Found: 102 active | as graph: single | with analogs [1] << Back 31 32 33 34 35 36 37 38 39 40  Next >> [102]
Species: 4932
Condition: HHF1
Replicates: 2
Raw OD Value: r im 0.1011±0.0153442
Normalized OD Score: sc h 0.1492±0.0195452
Z-Score: -36.9945±0.802505
p-Value: 0
Z-Factor: 0.753811
Fitness Defect: INF
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:8|A9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.60 Celcius
Date:2008-04-15 YYYY-MM-DD
Plate CH Control (+):0.04105±0.00054
Plate DMSO Control (-):0.68275±0.03359
Plate Z-Factor:0.7744
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 10748 | Additional Members: 6 | Rows returned: 3
SPE01505140 0.43859649122807
SPE01501017 0
LAT005C02 0

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