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Compound InformationSONAR Target prediction
Name:

CURCUMIN

Unique Identifier:SPE01505345
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C21H20O6
Molecular Weight:348.221 g/mol
X log p:  (online calculus)
Lipinksi Failures
TPSA
Hydrogen Bond Donor Count:
Hydrogen Bond Acceptors Count:
Rotatable Bond Count:
Canonical Smiles:COc1cc(C=CC(O)=CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O
Class:aromatic
Source:Curcuma spp
Reference:Ber 51: 1347 (1918); J Pharm Pharmacol 5: 448 (1953); Cancer Res 51:813 (1991)
Therapeutics:antiedemic, antiinflammatory, bile stimulant; antibacterial, antifungal,
lipo/cyclooxygenase inhibitor

Found: 102 active | as graph: single | with analogs [1] << Back 91 92 93 94 95 96 97 98 99 100  Next >> [102]
Species: 4932
Condition: NPR1
Replicates: 2
Raw OD Value: r im 0.7661±0.0897318
Normalized OD Score: sc h 0.7614±0.0859922
Z-Score: -6.2508±3.46566
p-Value: 0.0000722818
Z-Factor: -0.457068
Fitness Defect: 9.5349
Bioactivity Statement: Outlier
Experimental Conditions
Library:Spectrum_ED
Plate Number and Position:20|H4
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:30.00 Celcius
Date:2012-09-18 YYYY-MM-DD
Plate CH Control (+):0.0017499999999999998±0.00077
Plate DMSO Control (-):1.001375±0.02930
Plate Z-Factor:0.9004
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 10748 | Additional Members: 6 | Rows returned: 3
SPE01505140 0.43859649122807
SPE01501017 0
LAT005C02 0

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