| Compound Information | SONAR Target prediction | | Name: | 3,3--DIINDOLYLMETHANE | | Unique Identifier: | SPE01505331 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C17H14N2 | | Molecular Weight: | 232.195 g/mol | | X log p: | (online calculus) | | Lipinksi Failures | | | TPSA | | | Hydrogen Bond Donor Count: | | | Hydrogen Bond Acceptors Count: | | | Rotatable Bond Count: | | | Canonical Smiles: | C(c1cnc2ccccc12)c1cnc2ccccc12 | | Source: | synthetic | | Reference: | Biochem Biophys Res Commun 228:153 (1996) | | Therapeutics: | apoptosis inducer |
| Species: |
4932 |
| Condition: |
IRE1 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.4130±0.0311127 |
| Normalized OD Score: sc h |
0.5307±0.0266259 |
| Z-Score: |
-12.8698±0.324493 |
| p-Value: |
6.34238e-37 |
| Z-Factor: |
0.661009 |
| Fitness Defect: |
83.3484 |
| Bioactivity Statement: |
Active |
| Experimental Conditions | | | Library: | Spectrum_ED | | Plate Number and Position: | 23|F9 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 595 nm | | Robot Temperature: | 30.00 Celcius | | Date: | 2010-08-10 YYYY-MM-DD | | Plate CH Control (+): | 0.10200000000000001±0.00926 | | Plate DMSO Control (-): | 0.9315±0.02456 | | Plate Z-Factor: | 0.8911 |
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| DBLink | Rows returned: 0 | |
| internal high similarity DBLink | Rows returned: 0 | |
| nonactive | Cluster 17959 | Additional Members: 13 | Rows returned: 3 | |
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