| Compound Information | SONAR Target prediction |
| Name: | RIFAXIMIN |
| Unique Identifier: | SPE01505321 |
| MolClass: | Checkout models in ver1.5 and ver1.0 |
| Molecular Formula: | C43H51N3O11 |
| Molecular Weight: | 734.474 g/mol |
| X log p: | (online calculus) |
| Lipinksi Failures | |
| TPSA | |
| Hydrogen Bond Donor Count: | |
| Hydrogen Bond Acceptors Count: | |
| Rotatable Bond Count: | |
| Canonical Smiles: | COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(O C(C)=O)C1C)c1n5C=CC(C)=Cc5nc1c4c3C2=O |
| Source: | semisynthetic |
| Reference: | Drugs 49:467 (1995) |
| Therapeutics: | antibacterial, RNA synthesis inhibitor |
| Found: 104 nonactive as graph: single | with analogs | [1] << Back 1 2 3 4 5 6 7 8 9 10 Next >> [104] |
| Species: | 4932 |
| Condition: | IRE1 |
| Replicates: | 2 |
| Raw OD Value: r im | 0.8460±0.0551543 |
| Normalized OD Score: sc h | 1.0289±0.00457475 |
| Z-Score: | 0.7955±0.15061 |
| p-Value: | 0.428964 |
| Z-Factor: | -1.60608 |
| Fitness Defect: | 0.8464 |
| Bioactivity Statement: | Nonactive |
| ps |
| DBLink | Rows returned: 0 |
| internal high similarity DBLink | Rows returned: 0 |
| active | Cluster 6557 | Additional Members: 7 | Rows returned: 3 |
| Prest1296 | 0.411764705882353 |
| SPE01500529 | 0 |
| Prest833 | 0 |
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