Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

21-ACETOXYPREGNENOLONE

Unique Identifier:SPE01505123
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C23H34O4
Molecular Weight:340.244 g/mol
X log p:  (online calculus)
Lipinksi Failures
TPSA
Hydrogen Bond Donor Count:
Hydrogen Bond Acceptors Count:
Rotatable Bond Count:
Canonical Smiles:CC(=O)OCC(=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC21C
Class:sterol
Source:semisynthetic
Reference:PNAS 94:4895 (1997)
Therapeutics:precursor in corticoid biosynthesis, derivative

Found: 37 active | as graph: single | with analogs [1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [37]
Species: 4932
Condition: SSE1
Replicates: 2
Raw OD Value: r im 0.5395±0.0164756
Normalized OD Score: sc h 1.3037±0.0681382
Z-Score: 8.1079±1.34777
p-Value: 0.000000000000418742
Z-Factor: -0.30696
Fitness Defect: 28.5015
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:8|C9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.60 Celcius
Date:2008-05-01 YYYY-MM-DD
Plate CH Control (+):0.041±0.00107
Plate DMSO Control (-):0.397525±0.02290
Plate Z-Factor:0.8213
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 7902 | Additional Members: 9 | Rows returned: 6
Prest1157 0.405797101449275
SPE00270029 0.405797101449275
SPE01500645 0.276923076923077
Prest859 0.276923076923077
LOPAC 00530 0.227272727272727
SPE01505713 0.205882352941177

Service provided by the Mike Tyers Laboratory