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Compound InformationSONAR Target prediction
Name:

PODOPHYLLOTOXIN ACETATE

Unique Identifier:SPE01504412
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:432.251 g/mol
X log p:10.58  (online calculus)
Lipinksi Failures1
TPSA98.75
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:9
Rotatable Bond Count:6
Canonical Smiles:COc1cc(cc(OC)c1OC)C1C2C(COC2=O)C(OC(C)=O)c2cc3OCOc3cc12
Class:lignan
Source:derivative

Found: 205 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [205]
Species: 4932
Condition: BIK1
Replicates: 2
Raw OD Value: r im 0.6781±0.0059397
Normalized OD Score: sc h 0.9865±0.00493523
Z-Score: -0.5940±0.221005
p-Value: 0.557314
Z-Factor: -11.8273
Fitness Defect: 0.5846
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:5|G3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.70 Celcius
Date:2007-11-08 YYYY-MM-DD
Plate CH Control (+):0.0406±0.00107
Plate DMSO Control (-):0.672175±0.02435
Plate Z-Factor:0.8754
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DBLink | Rows returned: 6
164791
185985
225919
225920
233299
510879

internal high similarity DBLink | Rows returned: 1
SPE01504411 1.0000

active | Cluster 2906 | Additional Members: 14 | Rows returned: 0
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