| Compound Information | SONAR Target prediction | | Name: | MELOXICAM SODIUM | | Unique Identifier: | SPE01504150 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | | | Molecular Weight: | 338.3 g/mol | | X log p: | 10.452 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 100.49 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 7 | | Rotatable Bond Count: | 3 | | Canonical Smiles: | CN1C(C(=O)Nc2sc(C)cn2)=C(O)c2ccccc2S1(=O)=O | | Source: | synthetic | | Reference: | Neuropharmacol 39: 1653 (2000) | | Therapeutics: | antiinflammatory |
| Species: |
4932 |
| Condition: |
PDE1 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.8249±0.00608112 |
| Normalized OD Score: sc h |
1.0080±0.00281925 |
| Z-Score: |
0.2854±0.091273 |
| p-Value: |
0.77579 |
| Z-Factor: |
-9.72892 |
| Fitness Defect: |
0.2539 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Spectrum | | Plate Number and Position: | 21|F8 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 25.10 Celcius | | Date: | 2006-05-11 YYYY-MM-DD | | Plate CH Control (+): | 0.037925±0.00200 | | Plate DMSO Control (-): | 0.7871±0.01391 | | Plate Z-Factor: | 0.9306 |
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ps
pdf |
| DBLink | Rows returned: 1 | |
| 4051 |
sodium
9-methyl-8-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-10,10-dioxo-10$l^{6}-thia-9-azabicyclo[4.4.0]deca-1,3,
5,7-tetraen-7-olate |
| internal high similarity DBLink | Rows returned: 1 | |
| active | Cluster 16469 | Additional Members: 9 | Rows returned: 4 | |
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